THE PROTECTIVE EFFECT OF LOCAL BONE MARROW ASPHYXIA IN ACUTE RADIATION SICKNESS IN ANIMALS

Journal Article · Sat Oct 01 04:00:00 EDT 1960 · Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR

OSTI ID:4101687

Zherebchenko, P G; Krasnykh, I G; Lebkova, N P; Yarmonenko, S P

In experiments on mice, rats, and dogs, a study was made of the effect of local bone marrow asphyxia on the course and outcome of radiation sickness. Asphyxia was induced by applying a hemostatic tourniquet on the extremity of animals during irradiation. It was established that local asphyxia of the bone marrow alleviates the severity of acute radiation sickness and increases the survival of animals. It is shown that at the basis of the radioprotective action lies the reduced degeneration of the bone marrow, subsequently facilitating the regeneration of hematopeiesis. Data are obtained relative to the intensification of the effect of local asphyxia with the aid of prophylactic (mercamine) and curative (streptomycin) agents. (auth)

• Research Organization: Originating Research Org. not identified
• NSA Number: NSA-15-005916
• OSTI ID: 4101687
• Journal Information: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR, Journal Name: Meditsinskaya Radiologiya (U.S.S.R.) For English translation see Med. Radiol., USSR Vol. Vol: 5, No. 10; ISSN MERAA
• Country of Publication: Country unknown/Code not available
• Language: Russian

Related Subjects

AMINES
ANIMALS
ANTIBIOTICS
BIOLOGY AND MEDICINE
BLOOD VESSELS
BONE MARROW
DOGS
LIFETIME
MICE
RADIATION PROTECTION
RADIATION SICKNESS
RATS