A RADIOBIOLOGICAL ANALOGY BETWEEN MEASLES VIRUS AND TEMPERATE PHAGES

Journal Article · Wed Feb 01 00:00:00 EST 1961 · Proc. Natl. Acad. Sci. U.S.

DOI:https://doi.org/10.1073/pnas.47.2.213· OSTI ID:4094547

Ackerman, P H; Black, F L

Measles virus was found to be more resistant to ultraviolet (uv) than to ionizing radiations. The capacity of monkey kidney cells to grow unirradiated measles virus or measles virus irradiated with gamma rays was not affected appreciably by uv irradiation of the cells. However, the capacity of cells to grow uv irradiated virus was reduced by uv irradiation of the cells. In contrast, uv irradiation of cells did not affect their capacity to grow uv- treated polio virus. These effects of radiation on the measles virus system are analogous to effects on the phage P22 system and are compatible with the hypothesis of cellular repair of damaged virus previously suggested for the temperate phage. (auth)

• Research Organization: Yale Univ. School of Medicine, New Haven
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-010736
• OSTI ID: 4094547
• Journal Information: Proc. Natl. Acad. Sci. U.S., Vol. Vol: 47; Other Information: Orig. Receipt Date: 31-DEC-61
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ANIMAL CELLS
BACTERIOPHAGES
DISEASES
GAMMA RADIATION
KIDNEYS
MAN
MONKEYS
RADIOBIOLOGY
ULTRAVIOLET RADIATION
VIRUSES