THE ELECTROCHEMICAL PROPERTIES OF IMMUNE PROTEINS SYNTHESIZED IN AN IRRADIATED ORGANISM
Aggluttnins against Bact. paratyphi B. and precipitins against the proteins of human serum, which are produced in the healthy rabbit after the first injection of antigen, migrate in the electric field along with the gamma globulins. A third injection causes the appearance in the blood of the animals of an antibody with electrophoretic mobility of beta globulins. In the organism of rabbits irradiated with doses of 600 r, synthesis of antiparatyphoid agglutinins with the electrophoretic mobility of gamma and beta globulins was found. After the first injection of antigen in animals irradiated with a dose of 1000 r, agglutinins appeared in their blood which were localized in the gamma -, beta i-, and alpha /sub 2/-globulin fractions. The third injection of antigens caused formation of antibodies with the mobility of gamma globulins. Precipitins in the injured rabbits were localized only in the gamma -globulin fraction. (auth)
- Research Organization:
- State Medical Inst., Kursk, USSR
- NSA Number:
- NSA-15-012734
- OSTI ID:
- 4078991
- Journal Information:
- Biochemistry (U.S.S.R.) (English Translation), Journal Name: Biochemistry (U.S.S.R.) (English Translation) Vol. Vol: 25
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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