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THE TOLERANCE OF ANIMALS TO ACUTE COLD EXPOSURE FOLLOWING X-IRRADIATION

Technical Report ·
OSTI ID:4062988
A study was made to determine if x irradiation alters the tolerance of rats and guinea pigs to acute exposures of severe cold (-20 deg C) at various times after irradiation. It was found that the tolerance is lowered following irradiation. The cold tolemnce of rats varied inversely with radiation dose and the effect was present on the first day after sublethal doses of x rays. Following sublethal irradiation (400 r), the altered tolerance persisted through the eighteenth day and then disappeared. Following LD/sub 50/ exposures to x rays, the surviving rats exhibited a lowered cold tolerance at 6 months after irradiation. Ths role of body weight loss and possible mechanisms for the lowered cold tolerance following irradiation are discussed. (auth)
Research Organization:
Naval Radiological Defense Lab., San Francisco
NSA Number:
NSA-15-012725
OSTI ID:
4062988
Report Number(s):
USNRDL-TR-468
Country of Publication:
Country unknown/Code not available
Language:
English

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