X-RAY INDUCED SEX-LINKED LETHAL AND DETRIMENTAL MUTATIONS AND THEIR EFFECT ON THE VIABILITY OF DROSOPHILA MELANOGASTER

Journal Article · Wed Apr 01 04:00:00 EST 1964 · Genetics (U.S.)

OSTI ID:4056521

Friedman, L D

Tests were made on 2520 irradiated X chromosomes taken from Drosophila laboratory stocks of Basc and Carton-S strains. Estimates were made on the proportions of lethals and the genetic load of lethals and detrimentals induced. The Basc chromosome is about 50% more responsive to radioinduced lethal mutation than the Canton-S chromosome. It was found that the lethals induced in the + chromosome compared favorably with those tested by other workers, producing an average frequency of about 2.5% per 1000 r, The ratio of the load due to detrimental mutants to that for lethals was 0.125. This is where the load is the product of the frequency and the average effect on viability. This is a considerably lower value than was obtained in earlier experiments but is in general agreement with a recent study by Kafer. Possible reasons for the different results are discussed. (auth)

• Research Organization: Univ. of Wisconsin, Madison
• NSA Number: NSA-18-017520
• OSTI ID: 4056521
• Journal Information: Genetics (U.S.), Journal Name: Genetics (U.S.) Vol. Vol: 49; ISSN GENTA
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE