OSCILLATIONS OF THE NUCLEAR SIZES OF CELLS OF THE ADRENAL CORTEX IN RATS FOLLOWING IRRADIATION OF THE CORTEX AND OF THE PELVIS (in Italian)
The nuclear volume was studied in the zones of the adrenal cortex of rats whose adrenals had been irradiated directly and in rats in which the pelvis, but not the adrenals themselves had received a dose of 2000 r; the rats were sacrificed 5 hours, 24 hours, 5 days, and 30 days after irradiation. The following conclusions were drawn: ionizing radiation, whether administered directly to the adrenals or to the pelvis (but not the adrenals), gives rise to an increase in nuclear volume in all zones of the cortex; the increase is more pronounced in the outer zona fasciculata than in the zone reticularis. As already concluded by other authors, they affirm that increase in nuclear volume is the morphological expression of hyperactivity of the gland. After irradiation of the pelvis the neuro-endocrine effect produced by stress should predominate; after direct irradiation this effect should be partially neutralized by direct radiation damage. For this reason, increase in nuclear volume was more pronounced (especially in the zona fasciculata) in animals in which the pelvis had been irradiated and became more obvious 5 and 30 days after irradiation. (auth)
- Research Organization:
- Universita, Messina, Italy; Universita, Pavia; Italy and Ospedale Maggiore, Novara, Italy
- NSA Number:
- NSA-15-022136
- OSTI ID:
- 4044748
- Journal Information:
- Radiobiol. latina, Journal Name: Radiobiol. latina Vol. Vol: 3
- Country of Publication:
- Country unknown/Code not available
- Language:
- Italian
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