EFFECTS OF PREDNISOLONE ON THE SERUM LEVEL OF GLUTAMIC OXALACETIC TRANSAMINASE IN THE WHOLE-BODY IRRADIATED RABBIT

Journal Article · Fri Jan 01 04:00:00 EST 1960 · Radiobiol., radioterap. e fis. med.

OSTI ID:4025833

Parigi, G; Fantin, V; Vaccari, G L; Manzini, E; Bergonzini, R

As a supplement to a preceding study on the behavior of the values of glutamic oxalacetic transaminase in animals exposed to radiotherapy, a study was made of the variation of the velues of this enzyme in rabbits after whole-body irradiation (total body dose of 800 and 1200 r) as a result of treatment with prednisolone. Modifications of the serum value of the enzyme were observed in animals exposed to 1200 r. The administration of the corticosteroid hormone, especially if given before the irradiation, causes a smaller increase in the enzyme level, at least in the first 72 hr of the study. The results and their probably pathogenic mechanisms are discussed. (tr-auth)

• Research Organization: Universita, Modena, Italy
• NSA Number: NSA-15-016850
• OSTI ID: 4025833
• Journal Information: Radiobiol., radioterap. e fis. med., Journal Name: Radiobiol., radioterap. e fis. med. Vol. Vol: (3) 15
• Country of Publication: Country unknown/Code not available
• Language: Italian

Related Subjects

BIOLOGY AND MEDICINE
BLOOD SERUM
BODY
ENZYMES
HORMONES
IRRADIATION
PREDNISONE
RABBITS
RADIOTHERAPY
WHOLE-BODY IRRADIATION