RADIATION-INDUCED HEMORRHAGIC DIATHESIS IN DOGS UNASSOCIATED WITH THROMBOCYTOPENIA: ASSOCIATION WITH AN INTRAVASCULAR PROTEIN-POLYSACCHARIDE PARTICLE
Journal Article
·
· Blood (U.S.)
OSTI ID:4024648
Significant thrombocytopenia is not present preterminally in dogs given appropriate doses of /sup 90/Y--DTPA irradiation. Neventheless, these animals have a severe hemorrhagic diathesis at postmortem examination. Dogs systemically irradiated with /sup 90/Y-DTPA, and having a terminal hemorrhagic diathesis, demonstrate an intravascular polysaccharide substance at postmortem examination. This polysaccharide has staining characteristics similar to those first reported by Andersen in dogs systemically irradiated with x rays, and more recently observed in the lesions of thrombotic thrombocytopenic purpura. (auth)
- Research Organization:
- Univ. of California, Berkeley
- NSA Number:
- NSA-18-019600
- OSTI ID:
- 4024648
- Journal Information:
- Blood (U.S.), Journal Name: Blood (U.S.) Vol. Vol: 23; ISSN BLOOA
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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