MEASUREMENT OF ABSORPTION OF VITAMIN B$sub 12$ BY WHOLE-BODY GAMMA SPECTROMETRY
Journal Article
·
· Blood (U.S.)
OSTI ID:4024564
A technic is described to measure directly the intestinal absorption of radiovitamin B/sub 12/ by using a whole-body gamma spectrometer. A double tracer technic is used, and the amounts of free and intrinsic factor bound vitamin B/sub 12/, respectively, retained in the body after final excretion of unabsorbed radioactivity, are measured. The present method is simple and quantitative. The primary advantage of the whole-body counter for measuring absorption of Cobalt- labeled B/sub 12/ is that is can measure less than 0.1 mu c with a high degree of accuracy. Whole-body counting substitutes a rapid and simple measurement for the difficult and tedious collection and radiochemical analysis of excreta. (auth)
- Research Organization:
- Brookhaven National Lab., Upton, N.Y.
- NSA Number:
- NSA-15-024660
- OSTI ID:
- 4024564
- Report Number(s):
- BNL-5274; 0006-4971
- Journal Information:
- Blood (U.S.), Journal Name: Blood (U.S.) Vol. Vol: 18; ISSN BLOOA
- Country of Publication:
- United States
- Language:
- English
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