THE ASSAY OF THE TRANSPLANTATION POTENTIAL OF FRESH AND STORED BONE MARROW BY TWO IN-VIVO SYSTEMS

Journal Article · Tue Mar 31 00:00:00 EST 1964 · Annals of the New York Academy of Sciences (U.S.)

DOI:https://doi.org/10.1111/j.1749-6632.1964.tb53620.x· OSTI ID:4022074

Lewis, J P; Trobaugh, Jr, F E

The transplantation of isologous mouse marrow in the fresh and thawed state was compared in two in vivo systems. Both assay techniques indicate good survival of the basic repopulating unit after storage in 15% glycerol. The spleen colony technique is more efficient and sensitive than the studies of mouse protection. Presumably, both techniques depend upon the ability of the marrow to repopulate. Itilizing this colony-assay system, dimethyl suifoxide appears iess efficient than glycerol in protecting the basic repopulating unit. (auth)

• Research Organization: Presbyterian-St. Luke's Hospital, Chicago; and Univ. of Illinois, Chicago
• Sponsoring Organization: USDOE
• NSA Number: NSA-18-019777
• OSTI ID: 4022074
• Journal Information: Annals of the New York Academy of Sciences (U.S.), Vol. Vol: 114; Other Information: Orig. Receipt Date: 31-DEC-64
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ALCOHOLS
BONE MARROW
CHEMICALS
EFFICIENCY
GLYCERIN
LOW TEMPERATURE
METHYL RADICALS
MICE
PERFORMANCE
PRESERVATION
RADIATION PROTECTION
RECOVERY
REGENERATION
SPLEEN
STORAGE
SULFUR OXIDES
SURVIVAL TIME
TESTING
TRANSPLANTS
VARIATIONS