A SIMPLE METHOD FOR ESTABLISHING STABLE CONCENTRATIONS OF RADIOACTIVE CALCIUM, STRONTIUM AND PHOSPHORUS IN THE PLASMA OF GOATS AND COWS
A simple method for establishing a constant concentration of a radioactive tracer in the blood plasma for periods of several days or weeks is described. The method consists of the subcutaneous injection of a saline suspension of a sparingly soluble compound labeled with an isotope of the element concerned. This acts as a depot of radioactivity from which slow leaching occurs into the blood stream. In the case of Ca, calcium orthophosphate labeled with / sup 45/Ca was used as the depot, and for phosphorus the same compound labeled with /sup 32/P. Some experiments with Sr were also carried out using strontium sulfate labeled with /sup 45/Sr as the depot, and the princip1e may presumably be extended to other elements of biological interest. (P.C.H.)
- Research Organization:
- Argicultural Research Council Inst. for Research on Animal Diseases, Compton, Berks, Eng.
- Sponsoring Organization:
- USDOE
- NSA Number:
- NSA-18-019541
- OSTI ID:
- 4020164
- Journal Information:
- Nature, Journal Name: Nature Vol. Vol: 202
- Country of Publication:
- Country unknown/Code not available
- Language:
- English
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