A NEW METHOD FOR MASSIVE DUST EXPOSURES BY INHALATION

Journal Article · Sat Apr 01 00:00:00 EST 1961 · American Industrial Hygiene Association Journal (U.S.) Formerly Am. Ind. Hyg. Assoc. Q.

DOI:https://doi.org/10.1080/00028896109343379· OSTI ID:4019012

Macewen, J D; Urban, E C.J.; Smith, R G; Vorwald, A J

A chamber was designed which delivers a massive inhalation dose to anesthetized animals in a short period of time. The chamber consists of a vertically mounted cylinder with exposure ports arranged so that only the animals' heads are in the dust cloud. Studies were undertaken exposing Albino rats to strontium and rare earth oxides in the chamber. Data indicate that reproducible chamber concentrations are achieved, and that uniform pulmonary deposition of test material proportional to exposure time is accomplished. (auth)

• Research Organization: Wayne State Univ., Detroit
• Sponsoring Organization: USDOE
• NSA Number: NSA-15-017896
• OSTI ID: 4019012
• Journal Information: American Industrial Hygiene Association Journal (U.S.) Formerly Am. Ind. Hyg. Assoc. Q., Vol. Vol: 22; Other Information: Orig. Receipt Date: 31-DEC-61
• Country of Publication: Country unknown/Code not available
• Language: English

Related Subjects

BIOLOGY AND MEDICINE
ANESTHESIA
ANIMALS
DUSTS
LUNGS
QUANTITY RATIO
RARE EARTHS
RATS
STRONTIUM OXIDES