Allozyme genotype and survival of juvenile fathead minnows, Pimephales promelas, exposed to copper
- Miami Univ., Oxford, OH (United States)
Populations inhabiting contaminated areas have been Found to exhibit genetically based tolerance. Tolerance to a contaminant can only develop when appropriate genetic diversity exist in the stressed population. The effects of seven variable enzyme loci and multiple-locus heterozygosity on time to death (TTD) during an acute copper exposure were examined by creating two failure time regression models. Allozymes for five enzyme loci (Gpi-1, Gpi-2, ldh-1, Mdh-2, and Pgm) were significantly related to TTD. The model identified several resistant and sensitive allozyme genotypes. Heterozygosity was not related to TTD. Genetic diversity may be developed into a useful biomarker by monitoring frequency changes of sensitive genotypes.
- OSTI ID:
- 40081
- Report Number(s):
- CONF-9410273--
- Country of Publication:
- United States
- Language:
- English
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