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THE PRODUCTION OF CHROMATID ABERRATIONS BY DIEPOXYBUTANE AND AN IRON CHELATOR

Technical Report ·
OSTI ID:4003469
Preliminary studies showed that chromatid breaks produced by certain radiomimetic agents in combination do not interact to produce reunions. Results are reported from a series of studies on the roots of Vicia faba treated with radiomimetic agents and on iron chelator, x radiation, .1,2-3,4 diepoxybutane, or 2,2' bipyridine. Results tend to support a conclusion that the mode of action of nadiomimetic compounds is different from that of ionizing radiation. It is concluded that induced chromosome break rejoining may involve both a time factor and a consideration of the types of chemical bonds disrupted. (C.H.)
Research Organization:
Ohio Univ., Athens
NSA Number:
NSA-15-019157
OSTI ID:
4003469
Report Number(s):
TID-12720
Country of Publication:
United States
Language:
English

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