Role of glucose signaling in yeast metabolism
Journal Article
·
· Biotechnology and Bioengineering
OSTI ID:395137
- Univ. of Amsterdam (Netherlands). E.C. Slater Inst.
The conversion of glucose to ethanol and carbon dioxide by yeast was the first biochemical pathway to be studied in detail. The initial observation that this process is catalyzed by an extract of yeast led to the discovery of enzymes and coenzymes and laid the foundation for modern biochemistry. In this article, knowledge concerning the relation between uptake of and signaling by glucose in the yeast Saccharomyces cerevisiae is reviewed and compared to the analogous process in prokaryotes. It is concluded that (much) more fundamental knowledge concerning these processes is required before rational redesign of metabolic fluxes from glucose in yeast can be achieved.
- OSTI ID:
- 395137
- Journal Information:
- Biotechnology and Bioengineering, Vol. 52, Issue 1; Other Information: PBD: 5 Oct 1996
- Country of Publication:
- United States
- Language:
- English
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