Body contour determination and validation for Bremsstrahlung SPECT imaging

Journal Article · Fri Mar 01 04:00:00 EST 1996 · Journal of Nuclear Medicine

OSTI ID:394092

Siegel, J A; Khan, S H ^[1]

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1. Cooper Hospital/Univ. Medical Center, Camden, NJ (United States)

The purpose of this study was to validate a previously reported body contour measurement using Compton backscatter sources with bremsstrahlung SPECT imaging. Bremsstrahlung SPECT imaging was performed with {sup 32}P using a dual-headed camera system fitted with medium-energy, parallel-hole collimators. Two sources of {sup 99m}Tc were placed directly on each collimator. Energy windows of 100 keV {+-} 25% were used to image the {sup 32f}P and also to record the Compton scatter from the {sup 99m}Tc sources. Eleven patients enrolled in clinical Phase I therapeutic protocols were injected with {sup 32}P-chromic phosphate and SPECT images were acquired and reconstructed in the transaxial plane. The {sup 32}P distribution and the patient body contour were both visualized in these slices. The anteroposterior and lateral patient dimensions were measured by generating count profiles parallel to the anteroposterior and lateral body contour, respectively, at the midline in a transaxial slice. The distance in centimeters between the two centroids of each profile is representative of the anteroposterior and lateral dimensions and was determined for each patient. These anteroposterior and lateral dimensions were compared to the same distance measurements made in these patients by CT in an anatomically comparable transaxial slice. A cylindrical SPECT phantom was also studied to further validate the contour measurements. The mean percent difference in the patient dimension measurements between SPECT and CT was -0.8% with a range of -8.5% to 9.9%. The percent difference between the known and SPECT measured dimensions in the cylindrical phantom was 0.5%. The two external Compton scatter source method is accurate for determining the body contour. 20 refs., 2 figs., 1 tab.

• OSTI ID: 394092
• Journal Information: Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: 3 Vol. 37; ISSN JNMEAQ; ISSN 0161-5505
• Country of Publication: United States
• Language: English

Related Subjects

55 BIOLOGY AND MEDICINE
BASIC STUDIES
BODY
BRAIN
BREMSSTRAHLUNG
CHROMIUM COMPOUNDS
COLLIMATORS
DIMENSIONS
IMAGES
INJECTION
MASS DISTRIBUTION
NEOPLASMS
PATIENTS
PHOSPHATES
PHOSPHORUS 32
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY