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ODS: Overlapping oligonucleotide database with deductive engine for signal sequence search

Conference ·
OSTI ID:37539

There is a growing need for a well-designed database system for searching and analyzing nucleotide sequence data. The authors developed Overlapping Oligonucleotide Database for Signal Sequence Search (ODS), the first relational database that integrates information on biological features into the search for signal sequence. Furthermore, based on it, a deductive database system to search and analyze nucleotide sequence data was developed. Deductive database system is a next generation one and it contains an inference system. Database queries in ODS are described in both SQL and logical rules. These queries are simple even for molecular biologists who are not experts in computer programs. Particularly, queries based on logical rules are declarative and more powerful than those of SQL. Recursive rules are suitable for examining secondary structures of nucleotide sequences. In their analysis of TfR`s IRE, the authors noted five stem-and-loop structures.

OSTI ID:
37539
Report Number(s):
CONF-9206273--; ISBN 981-02-1157-0
Country of Publication:
United States
Language:
English

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