{sup 14}C-atrazine metaboite identification in field-grown sugarcane and sorghum by using radioactive detection and electrospray tandem mass spectrometry
- Corning Hazelton, Inc., Madison, WI (United States); and others
The metabolism of [2,4,6-{sup 14}C]-atrazine in field-grown sugarcane and sorghum produced several dechlorinated, dealkylated, and/or glutathione metabolites. These metabolites were identified by gas chromatography-mass spectrometry and electrospray-tandem mass spectrometry. The subsequent metabolism of glutathione adducts of atrazine and N-dealkylated atrazine to novel metabolites were studied. Lanthionine, lanthionine sulfoxide, glucose-thiolactate and glutamine adducts of atrazine are examples of metabolites that we postulate arise from a common intermediate metabolite of atrazine, i.e., atrazine-glutathione adduct at position 2. The mass spectra as well as the postulated metabolic pathways will be discussed. The identification of such metabolites at trace levels in plant tissues were made possible by the coupling of the radioactive detector and electrospray interface on-line to the tandem mass spectrometer.
- OSTI ID:
- 369967
- Report Number(s):
- CONF-960376--
- Country of Publication:
- United States
- Language:
- English
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