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Anaerobic dehalogenation of hydroxylated polychlorinated biphenyls by Desulfitobacterium dehalogenans

Journal Article · · Applied and Environmental Microbiology
OSTI ID:346836
; ;  [1]
  1. Univ. of Georgia, Athens, GA (United States). Dept. of Microbiology

Ten years after reports on the existence of anaerobic dehalogenation of polychlorinated biphenyls (PCBs) in sediment slurries, the authors report here on the rapid reductive dehalogenation of para-hydroxylated PCBs (HO-PCBs), the excreted main metabolites of PCB in mammals, which can exhibit estrogenic and antiestrogenic activities in humans. The anaerobic bacterium Desulfitobacterium dehalogenans completely dehalogenates all flanking chlorines (chlorines in ortho position to the para-hydroxyl group) from congeners such as 3,3{prime},5,5{prime}-tetrachloro-4,4{prime}-dihydroxybiphenyl.

OSTI ID:
346836
Journal Information:
Applied and Environmental Microbiology, Journal Name: Applied and Environmental Microbiology Journal Issue: 5 Vol. 65; ISSN AEMIDF; ISSN 0099-2240
Country of Publication:
United States
Language:
English

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