Plant rhamnogalacturonan II complexation of heavy metal cations
The present invention provides rhamnogalacturonan-II (RG-II) and relates to its ability to complex specific multivalent heavy metal cations. In the presence of boric acid, RG-II monomers form dimers that are cross-linked by a borate ester. The yield of such borate ester cross-linked dimers of RG-II is enhanced in the presence of specific heavy metal cations. The present invention further relates to the utility of RG-II in assays for the detection of specific heavy metal contamination; as a reagent useful in the removal of specific heavy metal cations contaminating foods and liquids, for example, fish, wines, etc.; as a pharmaceutical composition useful as an antidote in specific heavy metal cation poisoning; as a treatment for the detoxification of specific heavy metal cations from blood and/or tissues; and in a method of remediation of waters and soils contaminated with specific heavy metal cations. 15 figs.
- Research Organization:
- University of Georgia Research Foundation
- Sponsoring Organization:
- USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-93ER20097; FG05-93ER20115
- Assignee:
- Univ. of Georgia Research Foundation, Inc., Athens, GA (United States); Inst. National de la Recherche Agronomique, Paris (France)
- Patent Number(s):
- US 5,877,164/A/
- Application Number:
- PAN: 8-755,058
- OSTI ID:
- 335468
- Country of Publication:
- United States
- Language:
- English
Structural characterization of red wine rhamnogalacturonan II
|
journal | September 1996 |
Two Chains of Rhamnogalacturonan II Are Cross-Linked by Borate-Diol Ester Bonds in Higher Plant Cell Walls
|
journal | March 1996 |
Boron Nutrition of Cultured Tobacco BY-2 Cells. II. Characterization of the Boron-Polysaccharide Complex
|
journal | January 1997 |
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