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Bayesian analysis of MEG visual evoked responses

Technical Report ·
DOI:https://doi.org/10.2172/334231· OSTI ID:334231

The authors developed a method for analyzing neural electromagnetic data that allows probabilistic inferences to be drawn about regions of activation. The method involves the generation of a large number of possible solutions which both fir the data and prior expectations about the nature of probable solutions made explicit by a Bayesian formalism. In addition, they have introduced a model for the current distributions that produce MEG and (EEG) data that allows extended regions of activity, and can easily incorporate prior information such as anatomical constraints from MRI. To evaluate the feasibility and utility of the Bayesian approach with actual data, they analyzed MEG data from a visual evoked response experiment. They compared Bayesian analyses of MEG responses to visual stimuli in the left and right visual fields, in order to examine the sensitivity of the method to detect known features of human visual cortex organization. They also examined the changing pattern of cortical activation as a function of time.

Research Organization:
Los Alamos National Lab., NM (United States)
Sponsoring Organization:
National Insts. of Health, Bethesda, MD (United States)
DOE Contract Number:
W-7405-ENG-36
OSTI ID:
334231
Report Number(s):
LA-UR--99-630; CONF-990207--; ON: DE99002182
Country of Publication:
United States
Language:
English