Short-term effects of low-level winter pollution on respiratory health of asthmatic adults

Journal Article · Tue Sep 01 04:00:00 EDT 1998 · Archives of Environmental Health

DOI:https://doi.org/10.1080/00039899809605716· OSTI ID:302237

Neukirch, F; Segala, C; Korobaeff, M ^[1]; Le Moullec, Y ^[2]; Aubier, M ^[3]

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1. Inst. National de la Sante et de la Recherche Medicale, Paris (France)
2. Lab. d`Hygiene de la Ville, Paris (France)
3. Unite de Pneumologie Hopital Bichat, Paris (France)

The authors studied the short-term effects of Paris winter air pollution (i.e., sulfur dioxide, Black Smoke, suspended particulates with an aerodynamic diameter close to 10 {micro}m, and nitrogen dioxide) in 40 nonsmoking mild to moderate asthmatics. During a 6-mo period, subjects recorded asthma symptoms and three daily peak expiratory flow measurements. Statistical analysis revealed consistent and significant associations between the pollutants and asthma attacks and symptoms in the entire study group, especially in the subgroup of individuals who took inhaled {beta}2 agonists as needed. Pollutants correlated negatively with morning peak expiratory flow in the subgroup that took inhaled {beta}2 agonists as needed, and they correlated positively with daily variability in asthmatics who received regularly scheduled inhaled {beta}2 agonists. The effects lingered several days after exposure occurred. Low-level pollution has consistent measurable effects on nonsmoking adults who have well-treated mild or moderate asthma.

• Sponsoring Organization: USDOE
• OSTI ID: 302237
• Journal Information: Archives of Environmental Health, Journal Name: Archives of Environmental Health Journal Issue: 5 Vol. 53; ISSN AEHLAU; ISSN 0003-9896
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
56 BIOLOGY AND MEDICINE
APPLIED STUDIES
AIR POLLUTION
ASTHMA
FRANCE
HEALTH HAZARDS
NITROGEN DIOXIDE
PARTICULATES
SEASONAL VARIATIONS
SULFUR DIOXIDE