48Ca(p,pn)47Ca linac production for the preparation of a 47Ca/47Sc generator

Phipps, Michael D.; Kankanamalage, Pavithra H. A.; Lin, Wilson; Darienzo, Richard E.; Muench, Lisa; Vitkun, Christopher; Medvedev, Dmitri G.; Cutler, Cathy S.

doi:10.1016/j.apradiso.2025.112267

⁴⁸Ca(p,pn)⁴⁷Ca linac production for the preparation of a ⁴⁷Ca/⁴⁷Sc generator

Journal Article · Mon Nov 03 00:00:00 EST 2025 · Applied Radiation and Isotopes

DOI:https://doi.org/10.1016/j.apradiso.2025.112267· OSTI ID:3009100

^[1]; ^[1]; Lin, Wilson ^[1]; ^[1]; Muench, Lisa ^[1]; Vitkun, Christopher ^[1]; Medvedev, Dmitri G. ^[1]; ^[1]

Brookhaven National Laboratory (BNL), Upton, NY (United States)

Here, the production of ⁴⁷Sc via the nuclear reaction ⁴⁸Ca(p,pn)⁴⁷Ca→(β-, T_1/2 = 4.54 d)⁴⁷Sc and the assembly of a⁴⁷Ca/⁴⁷Sc generator system has been investigated at Brookhaven National Laboratory. To produce ⁴⁷Ca, a pressed ^natCaCl₂ target was irradiated with a proton beam at energy on target of 27.5 MeV at Brookhaven Linac Isotope Producer. Irradiated targets were dissolved in water and then acidified with concentrated HCl before separation using extraction chromatography through a diglycolamide (DGA) resin column. After ingrowth, ⁴⁷Sc was collected at >90 % with low contamination from both nonradioactive metals and coproduced radionuclides. A total of four ⁴⁷Ca/⁴⁷Sc separations were performed with 6–7 days between the irradiation and the separation to allow the equilibration of the ingrowing ⁴⁷Sc.

View Accepted Manuscript (DOE)

Research Organization:: Brookhaven National Laboratory (BNL), Upton, NY (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Nuclear Physics (NP)

Grant/Contract Number:: SC0012704

OSTI ID:: 3009100

Report Number(s):: BNL--229189-2025-JAAM

Journal Information:: Applied Radiation and Isotopes, Journal Name: Applied Radiation and Isotopes Vol. 228; ISSN 0969-8043

Publisher:: ElsevierCopyright Statement

Country of Publication:: United States

Language:: English

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