The Road Ahead for Metal–Organic Frameworks: Current Landscape, Challenges and Future Prospects

Barsoum, Michael L.; Fahy, Kira M.; Morris, William; Dravid, Vinayak P.; Hernandez, Benjamin; Farha, Omar K.

doi:10.1021/acsnano.4c14744

The Road Ahead for Metal–Organic Frameworks: Current Landscape, Challenges and Future Prospects

Journal Article · Fri Jan 03 00:00:00 EST 2025 · ACS Nano

DOI:https://doi.org/10.1021/acsnano.4c14744· OSTI ID:3007811

^[1]; ^[1]; Morris, William ^[2]; ^[1]; Hernandez, Benjamin ^[2]; ^[1]

Northwestern University, Evanston, IL (United States)
Numat Technologies, Chicago, IL (United States)

This perspective highlights the transformative potential of Metal–Organic Frameworks (MOFs) in environmental and healthcare sectors. It discusses work that has advanced beyond technology readiness levels of >4 including applications in capture, storage, and conversion of gases to value added products. This work showcases efforts in the most salient applications of MOFs which have been performed at a great cadence, enabled by the federal government, large companies, and startups to commercialize these technologies despite facing significant challenges. This article also forecasts the role of nanoscale MOFs in healthcare, including strides toward personalized medicine, advocating for their use in custom-tailored drug delivery systems. Lastly, we underscore the potential acceleration in MOF research and development through the integration of machine learning and AI, positioning MOFs as versatile tools poised to address global sustainability and health challenges.

View Accepted Manuscript (DOE)

Research Organization:: Northwestern University, Evanston, IL (United States); University of Chicago, IL (United States)

Sponsoring Organization:: National Science Foundation Graduate Research Fellowship (NSF GRFP); USDOE Office of Science (SC), Basic Energy Sciences (BES)

Grant/Contract Number:: SC0022332; SC0023383

OSTI ID:: 3007811

Journal Information:: ACS Nano, Journal Name: ACS Nano Journal Issue: 1 Vol. 19; ISSN 1936-0851; ISSN 1936-086X

Publisher:: American Chemical Society (ACS)Copyright Statement

Country of Publication:: United States

Language:: English

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