Mercury study report to Congress. Volume 4. Health effects of mercury and mercury compounds. Sab review draft
This volume of the draft Mercury Study Report to Congress summarizes the available information on human health effects and animal data for hazard identification and dose-response assessment for three forms of mercury: elemental mercury, mercury chloride (inorganic mercury), and methylmercury (organic mercury). Effects are summarized by endpoint. The risk assessment evaluates carcinogenicity, mutagenicity, developmental toxicity and general systemic toxicity of these chemical species of mercury. Toxicokinetics (absorption, distribution, metabolism and excretion) are described for each of the three mercury species. PBPK models are described, but not applied in risk assessment. Reference doses are calculated for inorganic and methylmercury; a reference concentration for inhaled elemental mercury is provided. A quantitiative analysis of factors contributing to variability and uncertainty in the methylmercury RfD is provided in an appendix. Interations and sensitive populations are described.
- Research Organization:
- Environmental Protection Agency, Research Triangle Park, NC (United States). Office of Air Quality Planning and Standards
- OSTI ID:
- 285172
- Report Number(s):
- PB-96-184650/XAB; EPA-452/R-96/001D; TRN: 62252399
- Resource Relation:
- Other Information: DN: See also Volume 3, PB--96-184643 and Volume 5, PB--96-184668; PBD: Jun 1996
- Country of Publication:
- United States
- Language:
- English
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