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A practical method for randoms subtraction in volume imaging PET from detector singles countrate measurements

Journal Article · · IEEE Transactions on Nuclear Science
DOI:https://doi.org/10.1109/23.507257· OSTI ID:276530
;  [1]
  1. Univ. of Pennsylvania, Philadelphia, PA (United States). Dept. of Radiology

Randoms subtraction in a volume imaging PET scanner is a significant problem due to the high singles countrates experienced. The delayed coincidence method requires double counting of randoms events and results in a lowered countrate capability. Calculations based on detector singles countrates require complex corrections for countrate dependent livetime and event acceptance due to the camera coincidence processing between the detector and rebinned randoms countrates. The profile distribution method has been used to estimate and subtract both scatter and randoms background but this method is a compromise and couples these 2 sources of background together. In order to avoid these problems and provide accurate subtraction of both the distribution and magnitude of randoms contamination in the scan data the authors have developed an alternative singles based method. The singles distributions are measured across the detectors and are used to construct a randoms distribution sinogram. This distribution is scaled to the appropriate rebinned randoms countrate by means of a lookup table of randoms countrate vs detector singles countrate, generated from phantom calibrations. The advantages of performing randoms subtraction by this method are: (1) there is no increase in camera deadtime, (2) the method compensates for nonuniformities in randoms distributions due to both the activity distribution and nonuniform geometric response of the camera for on and off bankpairs, and (3) it deals with randoms subtraction independently of scatter so that different scatter correction routines may then be applied to the data.

DOE Contract Number:
FG02-88ER60642
OSTI ID:
276530
Report Number(s):
CONF-951073--
Journal Information:
IEEE Transactions on Nuclear Science, Journal Name: IEEE Transactions on Nuclear Science Journal Issue: 3Pt2 Vol. 43; ISSN 0018-9499; ISSN IETNAE
Country of Publication:
United States
Language:
English

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