3D quantum ghost imaging microscope

Eshun, Audrey; Davenport, Dominique; Demory, Brandon; Kiannejad, Shervin; Mos, Paul; Lin, Yang; Bond, Tiziana; Rushford, Michael C.; Nuccio, Erin E.; Samo, Ty J.; Weber, Peter K.; Bruschini, Claudio; Charbon, Edoardo; Laurence, Ted A.

doi:10.1364/OPTICA.565248

3D quantum ghost imaging microscope

Journal Article · Tue Jul 15 00:00:00 EDT 2025 · Optica

DOI:https://doi.org/10.1364/OPTICA.565248· OSTI ID:2587623

^[1]; ^[1]; ^[1]; Kiannejad, Shervin ^[1]; Mos, Paul ^[2]; Lin, Yang ^[2]; Bond, Tiziana ^[1]; Rushford, Michael C. ^[1]; Nuccio, Erin E. ^[1]; ^[1]; ^[1]; ^[2]; ^[3]; ^[1]

Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)
Ecole Polytechnique Federale Lausanne (EPFL) (Switzerland)
Ecole Polytechnique Federale Lausanne (EPFL) (Switzerland). Centre de Recherche en Physique des Plasma (CRPP)

Quantum ghost imaging uses quantum-entangled photons to generate a two-dimensional image with only a bucket detector at the sample. Here we expand on this approach to generate a three-dimensional image without scanning. A quantum-entangled light source directly links information between a pair of 2D sensors, one of which captures a standard image from one perspective and a second sensor which captures a ghost image from a perpendicular perspective. By correlating the spatial information from the two detectors for each photon pair, we obtain three dimensions of spatial information (x, y, and z) for each scattered photon. We demonstrate that this system can study microscopic environments by imaging scattering from metallic nanoparticle clusters. This approach has the potential to greatly reduce the flux of light required to obtain a 3D image of a biological sample and thereby extend the number of images that can be obtained before photodamaging the sample.

View Accepted Manuscript (DOE)

Research Organization:: Lawrence Livermore National Laboratory (LLNL), Livermore, CA (United States)

Sponsoring Organization:: USDOE National Nuclear Security Administration (NNSA); USDOE Office of Science (SC), Biological and Environmental Research (BER)

Grant/Contract Number:: AC52-07NA27344

OSTI ID:: 2587623

Report Number(s):: LLNL--JRNL-2004733

Journal Information:: Optica, Journal Name: Optica Journal Issue: 7 Vol. 12; ISSN 2334-2536

Publisher:: Optica Publishing GroupCopyright Statement

Country of Publication:: United States

Language:: English

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