A novel cyclin gene (CCNF) in the region of the polycystic kidney disease gene (PKD1)
- Imperial Cancer Research Fund, London (United Kingdom); and others
The major locus for autosomal dominant polycystic kidney disease (PKD1) is located in a gene-rich region on chromosome 16p13.3. Recently the identification of the gene responsible for PKD1 has been described. While searching for candidate genes in this region, the authors isolated a new member of the cyclin family. They have characterized the transcript by sequencing, determination of the exon intron boundaries, and Northern blot analysis. Cyclin F is related to A- and B-type cyclins by sequence, but its function is unknown.
- OSTI ID:
- 255216
- Journal Information:
- Genomics, Journal Name: Genomics Journal Issue: 1 Vol. 24; ISSN 0888-7543; ISSN GNMCEP
- Country of Publication:
- United States
- Language:
- English
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