Rapid washout of technetium-99m-MIBI from a large parathyroid adenoma
Journal Article
·
· Journal of Nuclear Medicine
OSTI ID:255198
- Universite de Sherbrooke, Quebec (Canada); and others
The authors report a case of rapid {sup 99m}Tc-methoxyisobutylisonitrile (MIBI) clearance from a parathyroid adenoma. A double-phase {sup 99m}Tc-MIBI parathyroid scintigraphy was performed on a 62-yr-old female evaluated for primary hyperparathyroidism. A large parathyroid adenoma was visualized caudal to the left lobe of the thyroid gland with an unusually rapid washout of the tracer from tumor tissue. Histologic tissue examination confirmed the presence of a parathyroid adenoma and the absence of oxyphil cells. Care should be taken in interpretation of {sup 99m}Tc-MiBI parathyroid scintigrams because some adenomas can present a rapid release of the radiotracer in a double-phase study. Technitium-99m-MIBI retention could be related to the number of mitochondria-rich cells in parathyroid adenomas or to hyperplasia. 7 refs., 2 figs.
- OSTI ID:
- 255198
- Journal Information:
- Journal of Nuclear Medicine, Journal Name: Journal of Nuclear Medicine Journal Issue: 2 Vol. 36; ISSN JNMEAQ; ISSN 0161-5505
- Country of Publication:
- United States
- Language:
- English
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