Effects of macromolecular chelating agent on the release of {sup 239}Pu and {sup 59}Fe from rat alveolar macrophages after phagocytic uptake of {sup 239}Pu-{sup 59}Fe-iron hydroxide colloid
Journal Article
·
· Health Physics
- National Institute of Radiological Sciences, Chibashi (Japan); and others
The chelation-mediated mobilization of {sup 239}Pu and {sup 59}Fe from rat alveolar macrophages which had engulfed {sup 239}Pu-{sup 59}Fe-hydroxide colloids was studied by exposing the macrophages to diethylenetriaminepentaacetic acid and macromolecular weight forms of diethylenetriaminepentaacetic acid. The release of {sup 239}Pu and {sup 59}Fe by these macromolecular weight chelating agents and diethylenetriaminepentaacetic acid was assessed in monolayer culture and shown to be dependent upon the nature of the engulfed colloids. 25 refs., 4 tabs.
- Sponsoring Organization:
- USDOE
- OSTI ID:
- 249942
- Journal Information:
- Health Physics, Vol. 66, Issue 5; Other Information: PBD: May 1994
- Country of Publication:
- United States
- Language:
- English
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