Countries around the world have sought efficient protective coverings, including masks, gowns, and fabrics, for air purification to protect people against infectious diseases. However, the demand for significant quantities of disposable protective textiles poses a global challenge, especially when the production of protective gear is suspended due to COVID-19 outbreaks in factories and along supply lines. Therefore, the development of reusable, self-decontaminating protective masks and coverings loaded with disinfectants, such as antibacterial peroxide species, presents an attractive strategy to fight against bacteria risks. In this work, we incorporated persulfate ions, which serve as stable active peroxide precursors, into two porous zirconium-based metal–organic frameworks (Zr-MOFs), enabling these materials to act as regenerable reservoirs for the slow release of biocidal hydrogen peroxide upon hydrolysis by contact with humid air. Single-crystal X-ray diffraction studies reveal the two different coordination motifs for the persulfate ions, which can either bridge between two adjacent nodes or coordinate to a single node depending on both the node connectivity and the distances between open metal sites. The active peroxide precursors within the porous Zr-MOF carriers are stable during storage and easily regenerated once consumed. Importantly, these persulfate-loaded Zr-MOFs can be integrated onto textiles using a facile aqueous in-situ growth procedure, and these composites demonstrate potent and reusable biocidal activity against both Gram-negative bacteria and Gram-positive bacteria. Altogether, this approach presents a viable strategy to develop robust protective textiles capable of rapidly deactivating pathogens.
Ma, Kaikai, et al. "Zirconium-Based Metal–Organic Frameworks as Reusable Antibacterial Peroxide Carriers for Protective Textiles." Chemistry of Materials, vol. 35, no. 6, Mar. 2023. https://doi.org/10.1021/acs.chemmater.2c03288
Ma, Kaikai, Cheung, Yuk Ha, Xie, Haomiao, Wang, Xingjie, Evangelopoulos, Michael, Kirlikovali, Kent O., Su, Shengyi, Wang, Xiaoliang, Mirkin, Chad A., Xin, John H., & Farha, Omar K. (2023). Zirconium-Based Metal–Organic Frameworks as Reusable Antibacterial Peroxide Carriers for Protective Textiles. Chemistry of Materials, 35(6). https://doi.org/10.1021/acs.chemmater.2c03288
Ma, Kaikai, Cheung, Yuk Ha, Xie, Haomiao, et al., "Zirconium-Based Metal–Organic Frameworks as Reusable Antibacterial Peroxide Carriers for Protective Textiles," Chemistry of Materials 35, no. 6 (2023), https://doi.org/10.1021/acs.chemmater.2c03288
@article{osti_2480899,
author = {Ma, Kaikai and Cheung, Yuk Ha and Xie, Haomiao and Wang, Xingjie and Evangelopoulos, Michael and Kirlikovali, Kent O. and Su, Shengyi and Wang, Xiaoliang and Mirkin, Chad A. and Xin, John H. and others},
title = {Zirconium-Based Metal–Organic Frameworks as Reusable Antibacterial Peroxide Carriers for Protective Textiles},
annote = {Countries around the world have sought efficient protective coverings, including masks, gowns, and fabrics, for air purification to protect people against infectious diseases. However, the demand for significant quantities of disposable protective textiles poses a global challenge, especially when the production of protective gear is suspended due to COVID-19 outbreaks in factories and along supply lines. Therefore, the development of reusable, self-decontaminating protective masks and coverings loaded with disinfectants, such as antibacterial peroxide species, presents an attractive strategy to fight against bacteria risks. In this work, we incorporated persulfate ions, which serve as stable active peroxide precursors, into two porous zirconium-based metal–organic frameworks (Zr-MOFs), enabling these materials to act as regenerable reservoirs for the slow release of biocidal hydrogen peroxide upon hydrolysis by contact with humid air. Single-crystal X-ray diffraction studies reveal the two different coordination motifs for the persulfate ions, which can either bridge between two adjacent nodes or coordinate to a single node depending on both the node connectivity and the distances between open metal sites. The active peroxide precursors within the porous Zr-MOF carriers are stable during storage and easily regenerated once consumed. Importantly, these persulfate-loaded Zr-MOFs can be integrated onto textiles using a facile aqueous in-situ growth procedure, and these composites demonstrate potent and reusable biocidal activity against both Gram-negative bacteria and Gram-positive bacteria. Altogether, this approach presents a viable strategy to develop robust protective textiles capable of rapidly deactivating pathogens.},
doi = {10.1021/acs.chemmater.2c03288},
url = {https://www.osti.gov/biblio/2480899},
journal = {Chemistry of Materials},
issn = {ISSN 0897-4756},
number = {6},
volume = {35},
place = {United States},
publisher = {American Chemical Society (ACS)},
year = {2023},
month = {03}}