Single Molecule Tracking Studies of Lower Critical Solution Temperature Transition Behavior in Poly(N-isopropylacrylamide)

Elliott, Lindsay C.; Barhoum, Moussa; Harris, Joel M.; Bohn, Paul W.

doi:10.1021/la201753v

Single Molecule Tracking Studies of Lower Critical Solution Temperature Transition Behavior in Poly(N-isopropylacrylamide)

Journal Article · Tue Jul 19 00:00:00 EDT 2011 · Langmuir

DOI:https://doi.org/10.1021/la201753v· OSTI ID:2480681

Elliott, Lindsay C. ^[1]; Barhoum, Moussa ^[2]; Harris, Joel M. ^[2]; Bohn, Paul W. ^[3]

University of Illinois at Urbana−Champaign, IL (United States)
University of Utah, Salt Lake City, UT (United States)
University of Notre Dame, IN (United States)

Spatial and temporal heterogeneities in expanded and collapsed surface bound poly(N-isopropylacrylamide), pNIPAAm, films are studied by single molecule tracking (SMT) experiments. Tracking data are analyzed using both radius of gyration (R_g) evolution and confinement level calculations to elucidate the range of behaviors displayed by single Rhodamine6G (R6G) molecules. Furthermore, confined diffusion that is dictated by the free volume within surface tethered chains is observed with considerable dispersion among individual R6G molecules. Thus, the distribution of probe behavior reflects nanometer-scale information about the behavior of the probe–polymer system at temperatures above (T > T_LCST) and below (T < T_LCST) the lower critical solution temperature (LCST). In this context, confinement-level analysis and R_g evolution both show a larger degree of confinement of the probe in pNIPAAm at T > T_LCST. Temperature-dependent changes in confinement are evidenced at T > T_LCST by a higher percentage of confined steps, longer periods of confined events, and smaller area of confined zones, as well as a shift in the overall distribution of R_g evolution paths and final R_g distributions.

View Accepted Manuscript (DOE)

Research Organization:: University of Utah, Salt Lake City, UT (United States)

Sponsoring Organization:: USDOE Office of Science (SC), Basic Energy Sciences (BES). Chemical Sciences, Geosciences & Biosciences Division (CSGB); National Science Foundation (NSF)

Grant/Contract Number:: FG03-93ER14333

OSTI ID:: 2480681

Journal Information:: Langmuir, Journal Name: Langmuir Journal Issue: 17 Vol. 27; ISSN 0743-7463

Publisher:: American Chemical SocietyCopyright Statement

Country of Publication:: United States

Language:: English

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