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Causes of Death and Characteristics of Decedents With Viral Hepatitis, United States, 2010

Journal Article · · Clinical Infectious Diseases
DOI:https://doi.org/10.1093/cid/cit642· OSTI ID:2471281
 [1];  [1];  [1];  [1];  [1]
  1. Centers for Disease Control and Prevention (CDC), Atlanta, GA (United States)
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Previous research indicates that the mortality burden from viral hepatitis is growing, particularly among middle-aged persons. To monitor progress toward prevention goals, it is important to continue to document characteristics and comortalities of these deaths. This study sought to examine demographic characteristics and the most frequent causes of death among decedents with a viral hepatitis–related death. A cross-sectional study was performed on approximately 2.4 million death records from 2010. We calculated mortality rates for decedents with and without hepatitis A, B, and C virus (HAV, HBV, and HCV) and relative risks for the most frequently cited conditions in decedents with and without HBV and HCV. In 2010, there were 18 473 (0.7%) deaths with HAV, HBV, and HCV listed among causes of death, disproportionately in those aged 45–64 years. Among the 10 frequent causes of death, decedents listing HBV or HCV died, on average, 22–23 years earlier than decedents not listing these infections. HBV- and HCV-infected decedents aged 45–64 years had an increased risk of having the following conditions reported than decedents without these infections: cancer of liver and intrahepatic bile duct; fibrosis, cirrhosis, and other liver diseases; alcohol-related liver disease; gastrointestinal hemorrhage; human immunodeficiency infection; acute and unspecified renal failure; and septicemia (HCV only). Decedents with other causes of death that include HBV or HCV died 22–23 years earlier than decedents not listing these infections. These data suggest and support the need for prevention, early identification, and treatment of HBV and HCV.
Research Organization:
Oak Ridge Institute for Science and Education (ORISE), Oak Ridge, TN (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
Grant/Contract Number:
SC0014664
OSTI ID:
2471281
Journal Information:
Clinical Infectious Diseases, Journal Name: Clinical Infectious Diseases Journal Issue: 1 Vol. 58; ISSN 1058-4838
Publisher:
Oxford University PressCopyright Statement
Country of Publication:
United States
Language:
English

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Related Subjects

60 APPLIED LIFE SCIENCES
causes of death
death certificates
mortality
viral hepatitis