Effects of didecyldimethylammonium chloride on the biochemistry, swimming performance, gill histology and disease resistance of juvenile rainbow trout (Oncorhynchus mykiss)
- Simon Fraser Univ., Burnaby, British Columbia (Canada)
The acute lethal and sublethal toxicity of the antisapstain didecyldimethylammonium chloride (DDAC) to juvenile rainbow trout (Oncorhynchus mykiss) was investigated. The 96-h LC{sub 50} value in a flow-through exposure system was 0.4 mg-1{sup {minus}1}. Plasma cortisol, glucose and lactate levels were significantly elevated after an acute 24-h exposure to 0.4 mg-1{sup {minus}1}. Values for hepato-somatic index (HSI), haematocit, leucocrit, plasma haemoglobin, and liver glycogen remained unchanged. Swimming performance decreased significantly after exposure to 0.2 mg-1{sup {minus}1} for exposure durations of 12-h and 24-h and to 0.4 mg{sup {minus}1} for exposure durations of 12-h, 24-h, and 48-h. Scanning electron microscopic analysis revealed no gross lesions in gill epithelia as a result of toxicant exposure. In disease challenge experiments, exposure to sublethal concentrations of DDAC for 24-h did not effect the susceptibility of rainbow trout to the pathogen Vibrio anguilarum. Of a suite of toxicity tests, specific biochemical markers were unsatisfactory in revealing sublethal toxic effects. These were best revealed by an integrative measure of performance, namely swimming performance, but not disease resistance.
- OSTI ID:
- 244871
- Report Number(s):
- CONF-9511137--; ISBN 1-880611-03-1
- Country of Publication:
- United States
- Language:
- English
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