Challenges, progress, and future perspectives for cyanobacterial polyhydroxyalkanoate production

Rueda, Estel; Gonzalez-Flo, Eva; Mondal, Soumila; Forchhammer, Karl; Arias, Dulce María; Ludwig, Katharina; Drosg, Bernhard; Fritz, Ines; Gonzalez-Esquer, C. Raul; Pacheco, Sara; García, Joan

doi:10.1007/s11157-024-09689-0

Challenges, progress, and future perspectives for cyanobacterial polyhydroxyalkanoate production

Journal Article · Thu May 23 00:00:00 EDT 2024 · Reviews in Environmental Science and Bio/Technology

DOI:https://doi.org/10.1007/s11157-024-09689-0· OSTI ID:2426825

^[1]; Gonzalez-Flo, Eva ^[1]; Mondal, Soumila ^[2]; Forchhammer, Karl ^[2]; Arias, Dulce María ^[3]; Ludwig, Katharina ^[4]; Drosg, Bernhard ^[5]; Fritz, Ines ^[5]; ^[6]; ^[6]; ^[1]

Universitat Politècnica de Catalunya-BarcelonaTech, Barcelona (Spain)
Univ. of Tubingen (Germany)
Universidad Nacional Autónoma de México, Temixco (Mexico)
Bioenergy and Sustainable Technologies GmbH, Graz (Austria)
University of Natural Resources and Life Sciences, Vienna (Austria)
Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)

Polyhydroxyalkanoates (PHA) are a promising bio-based alternative to traditional plastics derived from petroleum. Cyanobacteria are photosynthetic organisms that produce PHA from CO₂ and sunlight, which can potentially reduce production costs and environmental footprint in comparison to heterotrophic bacteria cultures because (1) they utilize inorganic carbon sources for growth and (2) they do not require intensive aeration for oxygenation. Moreover, supplementing precursors such as propionate, acetate, valerate, etc., can be used to obtain various copolymers with plastic customizable properties in comparison to the classical homopolymers, such as polyhydroxybutyrate, PHB. This critical review covers the latest advances in PHA production, including recent discoveries in the metabolism interplay between PHA and glycogen production, and new insights into cultivation strategies that enhance PHA accumulation, and purification processes. This review also addresses the challenges and suggests potential solutions for a viable industrial PHAs production process.

View Accepted Manuscript (DOE)

Research Organization:: Los Alamos National Laboratory (LANL), Los Alamos, NM (United States)

Sponsoring Organization:: PROMICON; USDOE Laboratory Directed Research and Development (LDRD) Program

Grant/Contract Number:: 89233218CNA000001

OSTI ID:: 2426825

Report Number(s):: LA-UR--23-30430

Journal Information:: Reviews in Environmental Science and Bio/Technology, Journal Name: Reviews in Environmental Science and Bio/Technology Journal Issue: 2 Vol. 23; ISSN 1569-1705

Publisher:: Springer NatureCopyright Statement

Country of Publication:: United States

Language:: English

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59 BASIC BIOLOGICAL SCIENCES
Biological Science
Bioplastic
Bioplastics
Cyanobacteria
Metabolism
Microalgae
Optimization
PHA purification
PHB
Polyhdroxybutyrates
Wastewater

Challenges, progress, and future perspectives for cyanobacterial polyhydroxyalkanoate production

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