Assignment of the creatine transporter gene (SLC6A8) to human chromosome Xq28 telomeric to G6PD
- National Inst. on Drug Abuse, Baltimore, MD (United States)
- Duke Univ., Durham, NC (United States); and others
The creatine-phosphocreatine shuttle has important functions in the temporal and spatial maintenance of the energy supply to skeletal and cardiac muscle. Muscle cells do not synthesize creatine, but take it up via a specific sodium-dependent transporter - the creatine transporter. Thus, the creatine transporter has an important role in muscular physiology. Furthermore, inhibition of creatine transport in experimental animals causes muscle weakness. Recently, creatine transporter cDNAs have been isolated and characterized from rabbit and human. In this communication we report mapping of the creatine transporter gene to human chromosome Xq28. 12 refs., 1 fig.
- OSTI ID:
- 241108
- Journal Information:
- Genomics, Vol. 25, Issue 1; Other Information: PBD: 1 Jan 1995
- Country of Publication:
- United States
- Language:
- English
Similar Records
Identification of a testis-expressed creatine transporter gene at 16p11.2 and confirmation of the X-linked locus to Xq28
The genomic organization of a human creatine transporter (CRTR) gene located in Xq28
Cloning of a cDNA encoding a putative human very low density lipoprotein/Apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23[sup 6]
Journal Article
·
Wed May 15 00:00:00 EDT 1996
· Genomics
·
OSTI ID:241108
The genomic organization of a human creatine transporter (CRTR) gene located in Xq28
Journal Article
·
Mon Jul 15 00:00:00 EDT 1996
· Genomics
·
OSTI ID:241108
Cloning of a cDNA encoding a putative human very low density lipoprotein/Apolipoprotein E receptor and assignment of the gene to chromosome 9pter-p23[sup 6]
Journal Article
·
Mon Nov 01 00:00:00 EST 1993
· Somatic Cell and Molecular Genetics; (United States)
·
OSTI ID:241108
+3 more