MiNAA: Microbiome Network Alignment Algorithm
Journal Article
·
· Journal of Open Source Software
- Univ. of Wisconsin, Madison, WI (United States); University of Wisconsin-Madison Department of Plant Pathology
- Univ. of Wisconsin, Madison, WI (United States)
A microbial network is a mathematical representation of a microbial community where nodes represent microbes and edges represent interactions. It is well-recognized that microbes are among the main drivers of biological phenotypes in soil, plants, and animals alike, and thus, their study has vast implications for soil, plant and human health. In particular, recognizing the microbial, environmental, and agricultural factors that drive plant and soil phenotypes is crucial to comprehend processes connected to plant and soil health, to identify global practices of sustainable agriculture, as well as to predict plant and soil responses to environmental perturbations such as climate change. The adaptability of microbes to thrive in every environment poses challenges for scientists who try to understand their communities. Indeed, two microbial communities with the exact same players can interact differently depending on the environmental conditions. It is thus desirable to identify commonalities and differences on two microbial networks, hence the need for computational tools that can match (or align) them.
- Research Organization:
- Univ. of Wisconsin, Madison, WI (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Biological and Environmental Research (BER)
- Grant/Contract Number:
- SC0021016
- OSTI ID:
- 2395884
- Journal Information:
- Journal of Open Source Software, Journal Name: Journal of Open Source Software Journal Issue: 96 Vol. 9; ISSN 2475-9066
- Publisher:
- Open Source Initiative - NumFOCUSCopyright Statement
- Country of Publication:
- United States
- Language:
- English
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