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Dose Escalated Radiation Therapy for Glioblastoma Multiforme: An International Systematic Review and Meta-Analysis of 22 Prospective Trials

Journal Article · · International Journal of Radiation Oncology, Biology and Physics
 [1];  [2];  [3];  [4];  [3];
  1. Department of Radiation Oncology, Virginia Commonwealth University Health System, Richmond (United States)
  2. Department of Radiation Oncology, Icahn School of Medicine at Mount Sinai, New York, New York (United States)
  3. Department of Public Health Sciences, Penn State University, Hershey (United States)
  4. Department of Radiation Oncology, The James Cancer Hospital at the Ohio State University Wexner Medical Center, Columbus (United States)

Limited evidence is available on the utility of dose-escalated radiation therapy (DE-RT) with or without temozolomide (TMZ) versus standard-of-care radiation therapy (SoC-RT) for patients with newly diagnosed glioblastoma multiforme. We performed a systematic review/meta-analysis to compare overall survival (OS) and progression-free survival (PFS) between DE-RT and SoC-RT.

OSTI ID:
23200982
Journal Information:
International Journal of Radiation Oncology, Biology and Physics, Journal Name: International Journal of Radiation Oncology, Biology and Physics Journal Issue: 2 Vol. 111; ISSN IOBPD3; ISSN 0360-3016
Country of Publication:
United States
Language:
English

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