The burden of overall and cause-specific respiratory morbidity due to ambient air pollution in Sichuan Basin, China: A multi-city time-series analysis

Journal Article · Thu Nov 15 04:00:00 EST 2018 · Environmental Research

DOI:https://doi.org/10.1016/J.ENVRES.2018.08.011· OSTI ID:23100723

Qiu, Hang ^[1]; Yu, Haiyan ^[2]; Wang, Liya ^[1]; Zhu, Xiaojuan; Chen, Mengdie ^[1]; Zhou, Li ^[3]; Deng, Ren ^[3]; Zhang, Yanlong ^[4]; Pu, Xiaorong ^[1]; Pan, Jingping ^[3]

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1. Health Big Data Research Institute, Big Data Research Center, University of Electronic Science and Technology of China, Chengdu (China)
2. School of Economics and Management, Chongqing University of Posts and Telecommunications, Chongqing (China)
3. Health and Family Planning Information Center of Sichuan Province, Chengdu (China)
4. Chengdu Shulianyikang Technology Co., Ltd, Chengdu (China)

Highlights: • We assess the burden of respiratory HAs due to air pollution in Southwest China. • Risks of respiratory HAs were elevated following increased PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2}. • The effect estimates might be modified by age, season and region. • 1.84% of respiratory HAs were attributed to PM{sub 10}, 1.73% to PM{sub 2.5} and 0.34% to SO{sub 2}. Few studies have investigated the respiratory morbidity burden due to ambient air pollution in China, especially in a multi-city setting. This study aimed to estimate the short-term effects of ambient air pollutants (PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2}) on hospital admissions (HAs) for overall and cause-specific respiratory diseases, as well as the associated burden in 17 cities of Sichuan Basin, China during 2015–2016. Firstly, city-specific effect estimates for each pollutant on respiratory HAs were obtained using generalized additive model with quasi-Poisson link, and then random- or fixed-effects meta-analysis was applied to pool the effect estimates at the regional level. Subgroup analyses by sex, age, season and region were also performed. A total of 757,712 respiratory HAs were collected from all the tertiary and secondary hospitals located in the 17 cities. Risks of HAs for overall and cause-specific respiratory diseases were elevated following increased PM{sub 10}, PM{sub 2.5}, NO{sub 2} and SO{sub 2} exposure. An increase of 10 μg/m{sup 3} in PM{sub 10} at lag01, PM{sub 2.5} at lag01, NO{sub 2} at lag0 and SO{sub 2} at lag02 was associated with a 0.43% (95% CI: 0.33%, 0.53%), 0.53% (95% CI: 0.39%, 0.68%), 2.36% (95% CI: 1.75%, 2.98%) and 2.54% (95% CI: 1.51%, 3.59%) increases in total respiratory HAs, respectively. Children (≤ 14 years) and elderly (≥ 65 years) appeared to be more vulnerable to the effects of ambient air pollutants. Comparing to the WHO's air quality guidelines, we estimated that 1.84% (95%CI: 1.42%, 2.25%), 1.73% (95%CI: 1.27%, 2.19%) and 0.34% (95%CI: 0.21%, 0.48%) of respiratory HAs were due to PM{sub 10}, PM{sub 2.5} and SO{sub 2} exposure, respectively. This study suggests that air pollution might be an important trigger of respiratory admissions, and result in substantial burden of HAs for respiratory diseases in Sichuan Basin.

• OSTI ID: 23100723
• Journal Information: Environmental Research, Journal Name: Environmental Research Vol. 167; ISSN ENVRAL; ISSN 0013-9351
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
AIR POLLUTION
AIR QUALITY
CHILDREN
CHINA
DISEASE INCIDENCE
HEALTH HAZARDS
HOSPITALS
NITROGEN DIOXIDE
POLLUTANTS
PONDS
RECOMMENDATIONS
SEASONS
SULFUR DIOXIDE
TIME-SERIES ANALYSIS
URBAN AREAS