Calculated and Measured Dose Distributions in an Anthropomorphic RANDO Phantom - Paper 105

Conference · Mon Sep 15 00:00:00 EDT 2014

OSTI ID:23082927

Ramsey, Chester; Neeley, Michelle ^[1]

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1. Thompson Cancer Survival Center, 1915 White Ave, Knoxville, TN 37916 (United States)

Patient-specific quality assurance (QA) is a major component of the Intensity Modulated Radiation Therapy (IMRT) clinical process. The objective of this often time-intensive measurement process is to verify that the prescribed dose is accurately delivered to the target volume while sparing surrounding healthy tissue. The IMRT dose distributions can be measured using a wide variety of techniques and measurement devices including film (radiographic and radiochromic), ion chamber arrays, diode arrays, and Electronic Portal Imaging Devices (EPIDs). Of all the available modalities, film is one of the most versatile and most frequently utilized measurement systems. In rotation delivery techniques (such as volume modulated arc therapy and helical tomotherapy), composite dose distributions are obtained by irradiating a test phantom containing dosimeter(s). When film is utilized as the dosimeter, it can be placed in coronal, sagittal, or transverse planes inside the phantom. Because the film is irradiated using the rotational delivery sequence used to treat the patient, the dose given to specific anatomical structures (such as the parotids, spinal cord, bladder, rectum etc...) can be evaluated. Thomas et al (Med Phys 32: 3793-3800) recently reported the results of IMRT verifications for ten patients planned and treated with helical tomotherapy. This study reported that nearly 92% of the film pixels within the analyzed region of interest were within a gamma criterion of 2 mm and 2%. Like most tomotherapy users, Thomas et al used a test phantom made of homogeneous water equivalent material. Heterogeneous phantoms that simulate the different tissue densities in the human body do exist, but are infrequently used for patient-specific IMRT QA. The potential advantage of using heterogeneous phantoms is that the measured dose distributions will more adequately reflect the clinical dose distributions in the patients. The use of homogenous phantoms during IMRT quality assurance can potentially mask errors that arise from limitations in the treatment planning system's modeling of density corrections. The purpose of this study was to evaluate the dosimetric accuracy of a helical tomotherapy system using an anthropomorphic RANDO phantom (The Phantom Laboratory, Salem, NY) for patient-specific QA. The results of this study will allow a benchmark to be established for dosimetric accuracy in heterogeneous materials. Performing patient-specific QA is an integral part of the IMRT patient treatment process. Test phantoms are typically homogeneous, and do test the treatment planning systems ability to account for heterogeneity corrections. In this study, an anthropomorphic RANDO phantom was used to evaluate the doses calculated by a helical tomotherapy system. The dosimetric agreement between calculated and measured was worse than published results in homogenous phantoms, especially for target volumes located in the lung. Further investigation will be needed to determine if these errors are due to film response at heterogeneous tissue interfaces or from actual dose calculation errors. (authors)

• Research Organization: American Nuclear Society - ANS, 555 North Kensington Avenue, La Grange Park, IL 60526 (United States)
• OSTI ID: 23082927
• Resource Relation: Conference: RPSD 2014: 18. Topical Meeting of the Radiation Protection and Shielding Division of ANS, Knoxville, TN (United States), 14-18 Sep 2014; Other Information: Country of input: France; available on CD Rom from American Nuclear Society - ANS, 555 North Kensington Avenue, La Grange Park, IL 60526 (US)
• Country of Publication: United States
• Language: English

Related Subjects

61 RADIATION PROTECTION AND DOSIMETRY
62 RADIOLOGY AND NUCLEAR MEDICINE
ACCURACY
ANIMAL TISSUES
BENCHMARKS
BLADDER
CORRECTIONS
CT-GUIDED RADIOTHERAPY
DOSEMETERS
ERRORS
IONIZATION CHAMBERS
LUNGS
PATIENTS
PHANTOMS
QUALITY ASSURANCE
RADIATION DOSE DISTRIBUTIONS
RECTUM
SIMULATION
SPINAL CORD
VERIFICATION