Prophylactic Cranial Irradiation in Extensive Stage Small Cell Lung Cancer: Outcomes at a Comprehensive Cancer Centre

Journal Article · Wed Aug 15 04:00:00 EDT 2018 · International Journal of Radiation Oncology, Biology and Physics

DOI:https://doi.org/10.1016/J.IJROBP.2018.04.058· OSTI ID:23065541

Bang, Andrew; Kendal, Wayne S.; Cook, Graham; MacRae, Robert M. ^[1]; Laurie, Scott A. ^[2]

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1. Division of Radiation Oncology, University of Ottawa, Ottawa, Ontario (Canada)
2. Division of Medical Oncology, University of Ottawa, Ottawa, Ontario (Canada)

The role of prophylactic cranial irradiation (PCI) remains controversial in extensive stage small cell lung cancer (ES-SCLC) with the publication of 2 randomized control trials demonstrating differing outcomes in overall survival. The aim of this study is to determine the impact of PCI on survival and the development of brain metastasis while addressing the disparate use of postchemotherapy brain imaging in the aforementioned trials.

• OSTI ID: 23065541
• Journal Information: International Journal of Radiation Oncology, Biology and Physics, Journal Name: International Journal of Radiation Oncology, Biology and Physics Journal Issue: 5 Vol. 101; ISSN IOBPD3; ISSN 0360-3016
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
IRRADIATION
LUNGS
METASTASES
NEOPLASMS