PM2.5 Is Insufficient to Explain Personal PAH Exposure

Bramer, Lisa M.; Dixon, Holly M.; Rohlman, Diana; Scott, Richard P.; Miller, Rachel L.; Kincl, Laurel; Herbstman, Julie B.; Waters, Katrina M.; Anderson, Kim A.

doi:10.1029/2023gh000937

PM_2.5 Is Insufficient to Explain Personal PAH Exposure

Journal Article · Sat Feb 10 04:00:00 EST 2024 · GeoHealth

DOI:https://doi.org/10.1029/2023gh000937· OSTI ID:2299503

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Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
Oregon State University, Corvallis, OR (United States)
Icahn School of Medicine at Mount Sinai, New York, NY (United States)
Columbia University, New York, NY (United States)
Pacific Northwest National Laboratory (PNNL), Richland, WA (United States): Oregon State University, Corvallis, OR (United States)

To understand how chemical exposure can impact health, researchers need tools that capture the complexities of personal chemical exposure. In practice, fine particulate matter (PM_2.5) air quality index (AQI) data from outdoor stationary monitors and Hazard Mapping System (HMS) smoke density data from satellites are often used as proxies for personal chemical exposure, but do not capture total chemical exposure. Silicone wristbands can quantify more individualized exposure data than stationary air monitors or smoke satellites. However, it is not understood how these proxy measurements compare to chemical data measured from wristbands. In this study, participants wore daily wristbands, carried a phone that recorded locations, and answered daily questionnaires for a 7-day period in multiple seasons. We gathered publicly available daily PM_2.5 AQI data and HMS data. We analyzed wristbands for 94 organic chemicals, including 53 polycyclic aromatic hydrocarbons. Wristband chemical detections and concentrations, behavioral variables (e.g., time spent indoors), and environmental conditions (e.g., PM_2.5 AQI) significantly differed between seasons. Machine learning models were fit to predict personal chemical exposure using PM_2.5 AQI only, HMS only, and a multivariate feature set including PM_2.5 AQI, HMS, and other environmental and behavioral information. On average, the multivariate models increased predictive accuracy by approximately 70% compared to either the AQI model or the HMS model for all chemicals modeled. This study provides evidence that PM_2.5 AQI data alone or HMS data alone is insufficient to explain personal chemical exposures. Our results identify additional key predictors of personal chemical exposure.

View Accepted Manuscript (DOE)

Research Organization:: Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)

Sponsoring Organization:: USDOE Office of Science (SC); National Institute of Environmental Health Sciences (NIEHS); ARCS Foundation

Grant/Contract Number:: AC05-76RL01830

OSTI ID:: 2299503

Report Number(s):: PNNL-SA--184349

Journal Information:: GeoHealth, Journal Name: GeoHealth Journal Issue: 2 Vol. 8; ISSN 2471-1403

Publisher:: American Geophysical Union - WileyCopyright Statement

Country of Publication:: United States

Language:: English

References (55)

Comparison of wildfire smoke estimation methods and associations with cardiopulmonary-related hospital admissions: Estimates of Smoke and Health Outcomes Gan, Ryan W.; Ford, Bonne; Lassman, William GeoHealth, Vol. 1, Issue 3 https://doi.org/10.1002/2017gh000073	journal	May 2017
Simultaneous Inference in General Parametric Models Hothorn, Torsten; Bretz, Frank; Westfall, Peter Biometrical Journal, Vol. 50, Issue 3 https://doi.org/10.1002/bimj.200810425	journal	June 2008
A weighted random forests approach to improve predictive performance Winham, Stacey J.; Freimuth, Robert R.; Biernacka, Joanna M. Statistical Analysis and Data Mining: The ASA Data Science Journal, Vol. 6, Issue 6 https://doi.org/10.1002/sam.11196	journal	July 2013
Modern Applied Statistics with S Venables, W. N.; Ripley, B. D. Statistics and Computing https://doi.org/10.1007/978-0-387-21706-2	book	August 2002
An Introduction to Statistical Learning James, Gareth; Witten, Daniela; Hastie, Trevor Springer Texts in Statistics https://doi.org/10.1007/978-1-4614-7138-7	book	January 2013
PAHs in Gas and Particulate Phases: Measurement and Control Maharaj Kumari, K.; Lakhani, Anita Environmental Contaminants https://doi.org/10.1007/978-981-10-7332-8_3	book	November 2017
Chemical Composition of Wildland Fire Emissions Urbanski, Shawn P.; Hao, Wei Min; Baker, Stephen Wildland Fires and Air Pollution https://doi.org/10.1016/S1474-8177(08)00004-1	book	January 2008
Source profiles of volatile organic compounds (VOCs) measured in China: Part I Liu, Ying; Shao, Min; Fu, Linlin Atmospheric Environment, Vol. 42, Issue 25 https://doi.org/10.1016/j.atmosenv.2008.01.070	journal	August 2008
Phosphorus flame retardants: Properties, production, environmental occurrence, toxicity and analysis van der Veen, Ike; de Boer, Jacob Chemosphere, Vol. 88, Issue 10 https://doi.org/10.1016/j.chemosphere.2012.03.067	journal	August 2012
Unbiased split selection for classification trees based on the Gini Index Strobl, Carolin; Boulesteix, Anne-Laure; Augustin, Thomas Computational Statistics & Data Analysis, Vol. 52, Issue 1 https://doi.org/10.1016/j.csda.2006.12.030	journal	September 2007
Associations of wildfire smoke PM2.5 exposure with cardiorespiratory events in Colorado 2011–2014 Stowell, Jennifer D.; Geng, Guannan; Saikawa, Eri Environment International, Vol. 133 https://doi.org/10.1016/j.envint.2019.105151	journal	December 2019
Longer commutes are associated with increased human exposure to tris(1,3-dichloro-2-propyl) phosphate Reddam, Aalekhya; Tait, George; Herkert, Nicholas Environment International, Vol. 136 https://doi.org/10.1016/j.envint.2020.105499	journal	March 2020
Young children’s exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers Levasseur, Jessica L.; Hammel, Stephanie C.; Hoffman, Kate Environment International, Vol. 147 https://doi.org/10.1016/j.envint.2020.106317	journal	February 2021
Evaluating predictive relationships between wristbands and urine for assessment of personal PAH exposure Dixon, Holly M.; Bramer, Lisa M.; Scott, Richard P. Environment International, Vol. 163 https://doi.org/10.1016/j.envint.2022.107226	journal	May 2022
Silicone wristbands as personal passive sampling devices: Current knowledge, recommendations for use, and future directions Samon, Samantha M.; Hammel, Stephanie C.; Stapleton, Heather M. Environment International, Vol. 169 https://doi.org/10.1016/j.envint.2022.107339	journal	November 2022
A statistical model for determining impact of wildland fires on Particulate Matter (PM2.5) in Central California aided by satellite imagery of smoke Preisler, Haiganoush K.; Schweizer, Donald; Cisneros, Ricardo Environmental Pollution, Vol. 205 https://doi.org/10.1016/j.envpol.2015.06.018	journal	October 2015
Exposure of children and mothers to organophosphate esters: Prediction by house dust and silicone wristbands Xie, Qitong; Guan, Qingxia; Li, Liangzhong Environmental Pollution, Vol. 282 https://doi.org/10.1016/j.envpol.2021.117011	journal	August 2021
A systematic review of the physical health impacts from non-occupational exposure to wildfire smoke Liu, Jia C.; Pereira, Gavin; Uhl, Sarah A. Environmental Research, Vol. 136 https://doi.org/10.1016/j.envres.2014.10.015	journal	January 2015
Associations between wildfire smoke exposure during pregnancy and risk of preterm birth in California Heft-Neal, Sam; Driscoll, Anne; Yang, Wei Environmental Research, Vol. 203 https://doi.org/10.1016/j.envres.2021.111872	journal	January 2022
Polycyclic aromatic hydrocarbons in biomass-burning emissions and their contribution to light absorption and aerosol toxicity Samburova, Vera; Connolly, Jessica; Gyawali, Madhu Science of The Total Environment, Vol. 568 https://doi.org/10.1016/j.scitotenv.2016.06.026	journal	October 2016
Mixtures modeling identifies chemical inducers versus repressors of toxicity associated with wildfire smoke Rager, Julia E.; Clark, Jeliyah; Eaves, Lauren A. Science of The Total Environment, Vol. 775 https://doi.org/10.1016/j.scitotenv.2021.145759	journal	June 2021
Plant VOC emissions: making use of the unavoidable Penuelas, J. Trends in Ecology & Evolution, Vol. 19, Issue 8 https://doi.org/10.1016/j.tree.2004.06.002	journal	August 2004
Wildfire smoke and symptoms affecting mental health among adults in the U.S. state of Oregon Mirabelli, Maria C.; Vaidyanathan, Ambarish; Pennington, Audrey F. Preventive Medicine, Vol. 164 https://doi.org/10.1016/j.ypmed.2022.107333	journal	November 2022
How Do Indoor Environments Affect Air Pollution Exposure? Goldstein, Allen H.; Nazaroff, William W.; Weschler, Charles J. Environmental Science & Technology, Vol. 55, Issue 1 https://doi.org/10.1021/acs.est.0c05727	journal	December 2020
Wildfire Impact on Indoor and Outdoor PAH Air Quality Ghetu, Christine C.; Rohlman, Diana; Smith, Brian W. Environmental Science & Technology, Vol. 56, Issue 14 https://doi.org/10.1021/acs.est.2c00619	journal	July 2022
Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes Hammel, Stephanie C.; Hoffman, Kate; Webster, Thomas F. Environmental Science & Technology, Vol. 50, Issue 8 https://doi.org/10.1021/acs.est.6b00030	journal	March 2016
Characterization of Individual Isopropylated and tert -Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585 Phillips, Allison L.; Hammel, Stephanie C.; Konstantinov, Alex Environmental Science & Technology, Vol. 51, Issue 22 https://doi.org/10.1021/acs.est.7b04179	journal	November 2017
Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants Hammel, Stephanie C.; Phillips, Allison L.; Hoffman, Kate Environmental Science & Technology https://doi.org/10.1021/acs.est.8b03755	journal	October 2018
Comparing the Use of Silicone Wristbands, Hand Wipes, And Dust to Evaluate Children’s Exposure to Flame Retardants and Plasticizers Hammel, Stephanie C.; Hoffman, Kate; Phillips, Allison L. Environmental Science & Technology, Vol. 54, Issue 7 https://doi.org/10.1021/acs.est.9b07909	journal	March 2020
Monitoring Human Exposure to Organophosphate Esters: Comparing Silicone Wristbands with Spot Urine Samples as Predictors of Internal Dose Hoffman, Kate; Levasseur, Jessica L.; Zhang, Sharon Environmental Science & Technology Letters, Vol. 8, Issue 9 https://doi.org/10.1021/acs.estlett.1c00629	journal	August 2021
Indoor versus Outdoor Air Quality during Wildfires Messier, K. P.; Tidwell, L. G.; Ghetu, C. C. Environmental Science & Technology Letters, Vol. 6, Issue 12 https://doi.org/10.1021/acs.estlett.9b00599	journal	November 2019
Impact of the 2002 Canadian Forest Fires on Particulate Matter Air Quality in Baltimore City Sapkota, Amir; Symons, J. Morel; Kleissl, Jan Environmental Science & Technology, Vol. 39, Issue 1 https://doi.org/10.1021/es035311z	journal	November 2004
The Associations Between Clinical Respiratory Outcomes and Ambient Wildfire Smoke Exposure Among Pediatric Asthma Patients at National Jewish Health, 2012–2015 Lipner, Ettie M.; O'Dell, Katelyn; Brey, Steven J. GeoHealth, Vol. 3, Issue 6 https://doi.org/10.1029/2018gh000142	journal	June 2019
Differential Cardiopulmonary Health Impacts of Local and Long‐Range Transport of Wildfire Smoke Magzamen, Sheryl; Gan, Ryan W.; Liu, Jingyang GeoHealth, Vol. 5, Issue 3 https://doi.org/10.1029/2020gh000330	journal	February 2021
Associations Between Wildfire‐Related PM_2.5 and Intensive Care Unit Admissions in the United States, 2006–2015 Sorensen, Cecilia; House, John A.; O'Dell, Katelyn GeoHealth, Vol. 5, Issue 5 https://doi.org/10.1029/2021gh000385	journal	May 2021
Preparation and performance features of wristband samplers and considerations for chemical exposure assessment Anderson, Kim A.; Points, Gary L.; Donald, Carey E. Journal of Exposure Science & Environmental Epidemiology, Vol. 27, Issue 6 https://doi.org/10.1038/jes.2017.9	journal	July 2017
The National Human Activity Pattern Survey (NHAPS): a resource for assessing exposure to environmental pollutants Klepeis, Neil E.; Nelson, William C.; Ott, Wayne R. Journal of Exposure Science & Environmental Epidemiology, Vol. 11, Issue 3 https://doi.org/10.1038/sj.jea.7500165	journal	July 2001
Woodsmoke Health Effects: A Review Naeher, Luke P.; Brauer, Michael; Lipsett, Michael Inhalation Toxicology, Vol. 19, Issue 1 https://doi.org/10.1080/08958370600985875	journal	January 2007
A Community-Based Approach to Developing a Mobile Device for Measuring Ambient Air Exposure, Location, and Respiratory Health Rohlman, Diana; Syron, Laura; Hobbie, Kevin Environmental Justice, Vol. 8, Issue 4 https://doi.org/10.1089/env.2015.0001	journal	August 2015
Polycyclic Aromatic Hydrocarbons: From Metabolism to Lung Cancer Moorthy, Bhagavatula; Chu, Chun; Carlin, Danielle J. Toxicological Sciences, Vol. 145, Issue 1 https://doi.org/10.1093/toxsci/kfv040	journal	April 2015
Discovery of common chemical exposures across three continents using silicone wristbands Dixon, Holly M.; Armstrong, Georgina; Barton, Michael Royal Society Open Science, Vol. 6, Issue 2 https://doi.org/10.1098/rsos.181836	journal	February 2019
Use of multiple satellite sensors in NOAA's operational near real-time fire and smoke detection and characterization program Ruminski, Mark; Simko, John; Kibler, Jamie SPIE Proceedings https://doi.org/10.1117/12.807507	conference	August 2008
Warming and Earlier Spring Increase Western U.S. Forest Wildfire Activity Westerling, A. L. Science, Vol. 313, Issue 5789 https://doi.org/10.1126/science.1128834	journal	August 2006
Use of solid-phase microextraction as a sampling technique for the characterization of volatile compounds emitted from Chinese daffodil flowers Song, G.; Xiao, J.; Deng, C. Journal of Analytical Chemistry, Vol. 62, Issue 7 https://doi.org/10.1134/s1061934807070118	journal	July 2007
Air pollution from biomass burning and asthma hospital admissions in a sugar cane plantation area in Brazil Arbex, M. A.; Martins, L. C.; de Oliveira, R. C. Journal of Epidemiology & Community Health, Vol. 61, Issue 5 https://doi.org/10.1136/jech.2005.044743	journal	May 2007
Cardiovascular and Cerebrovascular Emergency Department Visits Associated With Wildfire Smoke Exposure in California in 2015 Wettstein, Zachary S.; Hoshiko, Sumi; Fahimi, Jahan Journal of the American Heart Association, Vol. 7, Issue 8 https://doi.org/10.1161/jaha.117.007492	journal	April 2018
Out‐of‐Hospital Cardiac Arrests and Wildfire‐Related Particulate Matter During 2015–2017 California Wildfires Jones, Caitlin G.; Rappold, Ana G.; Vargo, Jason Journal of the American Heart Association, Vol. 9, Issue 8 https://doi.org/10.1161/jaha.119.014125	journal	April 2020
Evaluation of a Wildfire Smoke Forecasting System as a Tool for Public Health Protection Yao, Jiayun; Brauer, Michael; Henderson, Sarah B. Environmental Health Perspectives, Vol. 121, Issue 10 https://doi.org/10.1289/ehp.1306768	journal	October 2013
Short-Term Exposure to Wildfire Smoke and PM2.5 and Cognitive Performance in a Brain-Training Game: A Longitudinal Study of U.S. Adults Cleland, Stephanie E.; Wyatt, Lauren H.; Wei, Linda Environmental Health Perspectives, Vol. 130, Issue 6 https://doi.org/10.1289/ehp10498	journal	June 2022
Impact of acute temperature and air pollution exposures on adult lung function: A panel study of asthmatics Evoy, Richard; Kincl, Laurel; Rohlman, Diana PLOS ONE, Vol. 17, Issue 6 https://doi.org/10.1371/journal.pone.0270412	journal	June 2022
Fitting Linear Mixed-Effects Models Using lme4 Bates, Douglas; Mächler, Martin; Bolker, Ben Journal of Statistical Software, Vol. 67, Issue 1 https://doi.org/10.18637/jss.v067.i01	journal	January 2015
Impact of Wildfire Smoke on Adverse Pregnancy Outcomes in Colorado, 2007–2015 Abdo, Mona; Ward, Isabella; O’Dell, Katelyn International Journal of Environmental Research and Public Health, Vol. 16, Issue 19 https://doi.org/10.3390/ijerph16193720	journal	October 2019
Differences in the Estimation of Wildfire-Associated Air Pollution by Satellite Mapping of Smoke Plumes and Ground-Level Monitoring Fadadu, Raj P.; Balmes, John R.; Holm, Stephanie M. International Journal of Environmental Research and Public Health, Vol. 17, Issue 21 https://doi.org/10.3390/ijerph17218164	journal	November 2020
Research Design & Statistical Analysis Myers, Jerome L.; Well, Arnold D. https://doi.org/10.4324/9781410607034	book	May 1995
09 Navamani, S. Johnson; Narayanasamy, G.; Premkumar, P. Sumithraj IOSR Journal of Applied Physics, Vol. 09, Issue 04 https://doi.org/10.9790/4861-0904020709	journal	July 2017

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