Novel Biocide Based on Cationic Derivative of Psyllium: Surface Modification and Antibacterial Activity
- Birla Institute of Technology, Mesra, Department of Chemistry (India)
- The University of Burdwan, Department of Botany, UGC-Centre of Advanced Study (India)
To circumvent the problems (such as volatilization, photolytic decomposition, chemical instability, easy permeability through the skin) associated with low molecular weight antimicrobial agents, our strategy employed graft copolymerization of cationic monomer with the polymeric substrate viz. psyllium husk. The surface graft concentration of quaternary ammonium ion on psyllium was optimized by measuring the extent of grafting in the microwave-induced process. The surface modification of graft copolymers was evident by different physico–chemical techniques like {sup 13}C nuclear magnetic resonance (NMR), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), X-ray diffractometer (XRD), differential scanning calorimetry (DSC), Thermo gravimeteric analysis (TGA), and viscometric study. The synthesized water soluble product resulted good antibacterial activity against Gram positive Staphylococcus aureus and Bacillus anthracis but failed to produce any antibacterial activity against Gram negative Salmonella typhi and Escherichia coli. The reason to failure has been explained on the basis of differences in the electrokinetic property between Gram-positive and Gram-negative bacteria. Optimum minimum inhibitory concentration (MIC) for the polymeric grade which showed good biocidal effect evaluated by both zone of inhibition and absorbance is found at 1000 µg/ml.
- OSTI ID:
- 22977132
- Journal Information:
- Journal of Polymers and the Environment, Vol. 27, Issue 6; Other Information: Copyright (c) 2019 Springer Science+Business Media, LLC, part of Springer Nature; Country of input: International Atomic Energy Agency (IAEA); ISSN 1566-2543
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
ANTIMICROBIAL AGENTS
BACILLUS
CARBON 13
COPOLYMERIZATION
COPOLYMERS
ESCHERICHIA COLI
FOURIER TRANSFORM SPECTROMETERS
FOURIER TRANSFORMATION
INFRARED SPECTRA
MICROWAVE RADIATION
NUCLEAR MAGNETIC RESONANCE
SALMONELLA
SCANNING ELECTRON MICROSCOPY
STAPHYLOCOCCUS
THERMAL GRAVIMETRIC ANALYSIS
X RADIATION
X-RAY DIFFRACTION
X-RAY DIFFRACTOMETERS