Clinical Outcomes of Transcatheter Arterial Embolisation for Chronic Knee Pain: Mild-to-Moderate Versus Severe Knee Osteoarthritis

Journal Article · Fri Nov 15 04:00:00 EST 2019 · Cardiovascular and Interventional Radiology

DOI:https://doi.org/10.1007/S00270-019-02289-4· OSTI ID:22970452

Hwang, Jin Ho ^[1]; Kim, Dong Hyun; So, Young Ho ^[2]; Park, Jihong ^[3]; Cho, Soo Buem ^[4]; Kim, Jeong-Eun ^[5]; Kim, Young Jae ^[6]; Hur, Saebeom; Jae, Hwan Jun ^[7]

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1. Konkuk University School of Medicine, Department of Radiology (Korea, Republic of)
2. Seoul Metropolitan Government - Seoul National University Boramae Medical Center, Department of Radiology (Korea, Republic of)
3. Seoul National University Bundang Hospital, Department of Rehabilitation Medicine (Korea, Republic of)
4. Ewha Womans University, College of Medicine, Department of Radiology, Ewha Womans University Seoul Hospital (Korea, Republic of)
5. Hallym University Sacred Heart Hospital, Department of Radiology (Korea, Republic of)
6. Gachon University College of Medicine, Department of Biomedical Engineering (Korea, Republic of)
7. Seoul National University Hospital, Department of Radiology (Korea, Republic of)

Purpose: This retrospective study was conducted to compare the clinical outcomes of transcatheter arterial embolisation for chronic knee pain in patients with mild-to-moderate versus severe knee osteoarthritis. Materials and Methods: This study included patients (n = 41) who were refractory to conservative treatments and who underwent transcatheter arterial embolisation using imipenem/cilastatin sodium between June 2017 and July 2018. A total of 71 knees, including 30 bilateral cases, were treated and categorised into two groups according to the Kellgren–Lawrence grade: mild-to-moderate osteoarthritis (n = 59, Kellgren–Lawrence grade 1–3) and severe osteoarthritis (n = 12, Kellgren–Lawrence grade 4). The clinical outcomes were measured by the visual analogue scale score. Results: There were no significant differences in age, body mass index or baseline visual analogue scale scores between the two groups. The mean visual analogue scale scores in the mild-to-moderate osteoarthritis group were significantly decreased at 1 day, 1 week, 1 month, 3 months, and 6-months (5.5 at baseline vs. 3.2, 3.1, 2.9, 2.2, and 1.9, after treatment; all P = .00). These improvements were maintained at a mean of 10 ± 3 months (range 6–19 months) post-treatment. The visual analogue scale scores were significantly decreased in the severe osteoarthritis group for 1 month post-treatment (6.3 at baseline vs. 4.1, 4.1, and 4.4 at 1 day, 1 week, and 1 month; all P < .01). However, a decrease in pain was not statistically significant from 3 to 6 months (5.4 and 5.9 at 3 months and 6 months, respectively). Conclusion: Transcatheter arterial embolisation effectively relieved pain in patients with mild-to-moderate osteoarthritis. In patients with severe osteoarthritis, pain severity decreased for 1 month but gradually increased to the initial severity score within 3 months. Level of Evidence: 4, Case series.

• OSTI ID: 22970452
• Journal Information: Cardiovascular and Interventional Radiology, Journal Name: Cardiovascular and Interventional Radiology Journal Issue: 11 Vol. 42; ISSN 0174-1551; ISSN CAIRDG
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BIOMEDICAL RADIOGRAPHY
BONE JOINTS
PAIN
PATIENTS
SKELETAL DISEASES