Multi-modality molecular imaging of aortic aneurysms

Journal Article · Tue Aug 15 04:00:00 EDT 2017 · Journal of Nuclear Cardiology (Online)

DOI:https://doi.org/10.1007/S12350-017-0883-2· OSTI ID:22955072

Sadeghi, Mehran M. ^[1]

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1. Yale University School of Medicine, Section of Cardiovascular Medicine (United States)

Aneurysms of the thoracic and abdominal aorta are common and can be associated with significant morbidity and mortality when complications, including dissection, rupture, or thrombosis, occur. Current approaches to diagnosis and risk stratification rely on measurements of aneurysm size and rate of growth, often using various imaging modalities, which may be suboptimal in identifying patients at the highest and lowest risk of complications. Targeting the biological processes underlying aneurysm formation and expansion with molecular imaging offers an exciting opportunity to characterize aortic aneurysms beyond size and address current gaps in our approach to diagnosis and treatment. In this review, we summarize the epidemiology and biology of aortic aneurysms and highlight the role of molecular imaging in furthering our understanding of aneurysm pathogenesis and its potential future role in guiding management.

• OSTI ID: 22955072
• Journal Information: Journal of Nuclear Cardiology (Online), Journal Name: Journal of Nuclear Cardiology (Online) Journal Issue: 4 Vol. 24; ISSN 1532-6551
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
AORTA
DIAGNOSIS
DISEASE INCIDENCE
EPIDEMIOLOGY
HAZARDS
MORTALITY
PATHOGENESIS
PATIENTS
POSITRON COMPUTED TOMOGRAPHY
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
THROMBOSIS