2,6-Disubstituted 4-azidopyrimidines: synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy
Journal Article
·
· Russian Chemical Bulletin
- Russian Academy of Sciences, N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry of Siberian Branch (Russian Federation)
Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol{sup –1}; ΔS = 47—65 J mol{sup –1} К–1; Е{sub a} = 93—117 kJ mol{sup –1}; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent.
- OSTI ID:
- 22863435
- Journal Information:
- Russian Chemical Bulletin, Journal Name: Russian Chemical Bulletin Journal Issue: 11 Vol. 66; ISSN RCBUEY; ISSN 1066-5285
- Country of Publication:
- United States
- Language:
- English
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