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Association of hydrophilic derivatives of chlorophyll a in ethanol–water and ethanol–water–solubilizer systems

Journal Article · · Russian Chemical Bulletin
;  [1]; ;  [2]
  1. Research Institute of Macroheterocyclic Compounds, Ivanovo State University of Chemical Technology (Russian Federation)
  2. Ural Branch of the Russian Academy of Sciences, Institute of Chemistry, Komi Scientific Center (Russian Federation)
Electronic absorption spectroscopy and fluorescence spectroscopy were used to study conditions for the formation of associates of amphiphilic phorbins and chlorins in an ethanol–water system. The conditions and degree of disaggregation in the presence of solubilizing additives of nonionic surfactants (Tween 80) and biocompatible polymers (polyethylene glycol and polyvinylpyrrolidone) were also investigated. The propensity of the macroheterocycles based on chlorophyll a to association in water-alcoholic solutions decreases on going from covalently bound dimeric structures to monomeric ones, on going from phorbins to chlorins and on accumulating hydrophilic glycol or positively charged alkylammonium fragments in the molecule. Among the considered solubilizers, the nonionic surfactant Tween 80 emerged as the most efficient means for destroying chlorin associates in water–alcohol solutions with a high content of water.
OSTI ID:
22863316
Journal Information:
Russian Chemical Bulletin, Journal Name: Russian Chemical Bulletin Journal Issue: 7 Vol. 67; ISSN RCBUEY; ISSN 1066-5285
Country of Publication:
United States
Language:
English