Microstructure, Mechanical Properties and Corrosion Behavior of Porous Mg-6 wt.% Zn Scaffolds for Bone Tissue Engineering

Journal Article · Thu Mar 15 04:00:00 EDT 2018 · Journal of Materials Engineering and Performance

DOI:https://doi.org/10.1007/S11665-018-3189-X· OSTI ID:22858043

Yan, Yang ^[1]; Kang, Yijun; Li, Ding ^[2]; Yu, Kun ^[1]; Xiao, Tao; Wang, Qiyuan; Deng, Youwen ^[2]; Fang, Hongjie ^[3]; Jiang, Dayue; Zhang, Yu ^[1]

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1. Central South University, School of Materials Science and Engineering (China)
2. Central South University, The Second Xiangya Hospital (China)
3. Yantai Nanshan University, Department of Materials Science and Engineering (China)

Porous Mg-based scaffolds have been extensively researched as biodegradable implants due to their attractive biological and excellent mechanical properties. In this study, porous Mg-6 wt.% Zn scaffolds were prepared by powder metallurgy using ammonium bicarbonate particles as space-holder particles. The effects of space-holder particle content on the microstructure, mechanical properties and corrosion resistance of the Mg-6 wt.% Zn scaffolds were studied. The mean porosity and pore size of the open-cellular scaffolds were within the range 6.7-52.2% and 32.3-384.2 µm, respectively. Slight oxidation was observed at the grain boundaries and on the pore walls. The Mg-6 wt.% Zn scaffolds were shown to possess mechanical properties comparable with those of natural bone and had variable in vitro degradation rates. Increased content of space-holder particles negatively affected the mechanical behavior and corrosion resistance of the Mg-6 wt.% Zn scaffolds, especially when higher than 20%. These results suggest that porous Mg-6 wt.% Zn scaffolds are promising materials for application in bone tissue engineering.

• OSTI ID: 22858043
• Journal Information: Journal of Materials Engineering and Performance, Journal Name: Journal of Materials Engineering and Performance Journal Issue: 3 Vol. 27; ISSN 1059-9495; ISSN JMEPEG
• Country of Publication: United States
• Language: English

Related Subjects

36 MATERIALS SCIENCE
BONE TISSUES
COMPARATIVE EVALUATIONS
CORROSION RESISTANCE
GRAIN BOUNDARIES
IMPLANTS
MAGNESIUM ALLOYS
MECHANICAL PROPERTIES
OXIDATION
POROSITY
POROUS MATERIALS
POWDER METALLURGY
SKELETON
ZINC COMPOUNDS