Evolution of brachytherapy treatment planning to deterministic radiation transport for calculation of cardiac dose

Journal Article · Fri Jun 15 00:00:00 EDT 2018 · Medical Dosimetry

DOI:https://doi.org/10.1016/J.MEDDOS.2018.02.014· OSTI ID:22824191

Feng, Yuntao ^[1]; Platt, Michael; Lamba, Michael ^[2]; Mahalingam, Sudha ^[3]

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1. OhioHealth-Radiation Oncology, Columbus, Ohio 43214 (United States)
2. College of Medicine, University of Cincinnati, Cincinnati, Ohio 45267 (United States)
3. American Brachytherapy Society and American Society for Radiation Oncology (United States)

Brachytherapy was among the first methods of radiotherapy and has steadily continued to evolve. Here we present a brief review of the progression of dose calculation methods in brachytherapy to the current state-of-the art computerized methods for heterogeneity correction. We further review the origin and development of the BrachyVision (Varian Medical Systems, Inc., Palo Alto, CA) treatment planning system and evaluate dosimetric results from 12 patients implanted with the strut-assisted volumetric implant (SAVI) applicator (Cianna Medical, Aliso Viejo, CA) for accelerated partial breast irradiation (APBI). Dosimetric results from plans calculated using homogenous and heterogeneous algorithms have been compared to investigate the impact of heterogeneity corrections. Our study showed large percent difference between mean cardiac doses 11.8 ± 6.2% (p = 0.0007) calculated with and without heterogeneity corrections. Our findings are consistent with those of others, indicating an overestimation of the distal dose to organs-at-risk by traditional methods, especially at interfaces between air and tissue.

• OSTI ID: 22824191
• Journal Information: Medical Dosimetry, Vol. 43, Issue 2; Other Information: Copyright (c) 2017 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.; Country of input: International Atomic Energy Agency (IAEA); ISSN 0958-3947
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ALGORITHMS
BRACHYTHERAPY
CALCULATION METHODS
CORRECTIONS
HEART
IMPLANTS
MAMMARY GLANDS
PLANNING
RADIATION DOSES
RADIATION TRANSPORT