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Immunity, immunotherapy, and rectal cancer: A clinical and translational science review

Journal Article · · Translational Research

Not Available

Sponsoring Organization:
USDOE
OSTI ID:
2279757
Journal Information:
Translational Research, Journal Name: Translational Research Journal Issue: C Vol. 231; ISSN 1931-5244
Publisher:
ElsevierCopyright Statement
Country of Publication:
Netherlands
Language:
English

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Potential immune priming of the tumor microenvironment with FOLFOX chemotherapy in locally advanced rectal cancer journal February 2018
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Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome journal September 2006
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Adverse Immunoregulatory Effects of 5FU and CPT11 Chemotherapy on Myeloid-Derived Suppressor Cells and Colorectal Cancer Outcomes journal October 2014
Acquired Resistance to Fractionated Radiotherapy Can Be Overcome by Concurrent PD-L1 Blockade journal September 2014
IDO1 and Kynurenine Pathway Metabolites Activate PI3K-Akt Signaling in the Neoplastic Colon Epithelium to Promote Cancer Cell Proliferation and Inhibit Apoptosis journal March 2019
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Blocking Indolamine-2,3-Dioxygenase Rebound Immune Suppression Boosts Antitumor Effects of Radio-Immunotherapy in Murine Models and Spontaneous Canine Malignancies journal August 2016
The Immune-microenvironment Confers Chemoresistance of Colorectal Cancer through Macrophage-Derived IL6 journal November 2017
Mismatch Repair–Deficient Rectal Cancer and Resistance to Neoadjuvant Chemotherapy journal July 2020
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The indoleamine 2,3-dioxygenase pathway controls complement-dependent enhancement of chemo-radiation therapy against murine glioblastoma journal January 2014
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Neoadjuvant Modified FOLFOX6 With or Without Radiation Versus Fluorouracil Plus Radiation for Locally Advanced Rectal Cancer: Final Results of the Chinese FOWARC Trial journal December 2019
Clinical Relevance of Microsatellite Instability in Colorectal Cancer journal July 2010
Capecitabine Plus Oxaliplatin Compared With Fluorouracil and Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer journal April 2011
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Capecitabine Plus Oxaliplatin Compared With Fluorouracil/Folinic Acid As Adjuvant Therapy for Stage III Colon Cancer: Final Results of the NO16968 Randomized Controlled Phase III Trial journal November 2015
Durable Clinical Benefit With Nivolumab Plus Ipilimumab in DNA Mismatch Repair–Deficient/Microsatellite Instability–High Metastatic Colorectal Cancer journal March 2018
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CD8+ and FOXP3+ Tumor-Infiltrating T Cells Before and After Chemoradiotherapy for Rectal Cancer journal February 2014
Predictors of Bowel Function in Long-term Rectal Cancer Survivors with Anastomosis journal August 2017
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Gamma-Ray Resistance of Regulatory CD4+CD25+Foxp3+T Cells in Mice journal February 2010
Up-regulation of the Pro-inflammatory Chemokine CXCL16 is a Common Response of Tumor Cells to Ionizing Radiation journal April 2010
Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients journal January 2015
Beyond microsatellite testing: assessment of tumor mutational burden identifies subsets of colorectal cancer who may respond to immune checkpoint inhibition journal August 2018
A comprehensive longitudinal overview of health-related quality of life and symptoms after treatment for rectal cancer in the TME trial journal September 2015
Cancer statistics, 2020 journal January 2020
Interferon-Gamma at the Crossroads of Tumor Immune Surveillance or Evasion journal May 2018
FOLFOX Chemotherapy Ameliorates CD8 T Lymphocyte Exhaustion and Enhances Checkpoint Blockade Efficacy in Colorectal Cancer journal April 2020
The Determination of Immunomodulation and Its Impact on Survival of Rectal Cancer Patients Depends on the Area Comprising a Tissue Microarray journal February 2020
Immunotherapy in colorectal cancer: Available clinical evidence, challenges and novel approaches journal August 2019
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Radiation-Induced IFN-γ Production within the Tumor Microenvironment Influences Antitumor Immunity journal March 2008
NCCN Guidelines Insights: Rectal Cancer, Version 6.2020 journal July 2020

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